Influence of Parental SUD and ADHD on ADHD in their Offspring: Preliminary Results from a Pilot-controlled Family Study
As part of a pilot-controlled family-based study of the children of parents with and without substance use disorders (SUD), the influence of parental SUD and ADHD on the risk for ADHD in offspring was evaluated. Using structured psychiatric interviews, 96 families (183 youth; mean age 11.6 years) we...
Gespeichert in:
| Veröffentlicht in: | The American journal on addictions 2005-03, Vol.14 (2), p.179-187 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 187 |
|---|---|
| container_issue | 2 |
| container_start_page | 179 |
| container_title | The American journal on addictions |
| container_volume | 14 |
| creator | Wilens, Timothy E. Hahesy, Amy L. Biederman, Joseph Bredin, Elizabeth Tanguay, Sarah Kwon, Anne Faraone, Stephen V. |
| description | As part of a pilot-controlled family-based study of the children of parents with and without substance use disorders (SUD), the influence of parental SUD and ADHD on the risk for ADHD in offspring was evaluated. Using structured psychiatric interviews, 96 families (183 youth; mean age 11.6 years) were assessed. To evaluate the effect of parental ADHD and SUD, the offspring were stratified into four groups based on parental status: children of parents with neither ADHD nor SUD, children of parents with SUD only, children of parents with ADHD only, and children of parents with both ADHD and SUD. Using generalized estimating equation models, parental SUD and ADHD were used to predict ADHD in the offspring. The rate of children with ADHD increased among children of parents with neither disorder (3%), children of parents with SUD (13%), children of parents with ADHD (25%), and children of parents with both ADHD and SUD (50%) (p = .001). Children of parents with ADHD or ADHD plus SUD were more likely to have ADHD in comparison to children of parents with neither diagnosis (p < 0.05). Children of parents with ADHD plus SUD were at greater risk of ADHD in comparison to children of parents with SUD only (p = 0.01). Despite the small sample size, the results of this study seem to suggest that the offspring of SUD or ADHD parents are at elevated risk for ADHD compared to controls. The offspring of parents with both ADHD and SUD appear to be at the highest risk for ADHD, highlighting the need for careful screening of this group of youth for ADHD. Replication studies clarifying the nature and strength of the association are necessary.(Am J Addict 2005;14:179-187) |
| doi_str_mv | 10.1080/10550490590924872 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_19613944</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19613944</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4673-c0777e7e9ab4f0cc3baac99d3c7a8cc8ff643c0db3f46390c7c4292f545623593</originalsourceid><addsrcrecordid>eNqFkc1uEzEUhUcIREvhAdggr9gN2OO_MayihrRFFY0IFYiN5Xhs4uKxW9ujkrfHaCJYIMHd3Cv5O0c6x03zHMFXCPbwNYKUQiIgFVB0pOfdg-YY0Q61EAv0sN71va0AO2qe5HwD6_SCPW6OEINICMaOm_uLYP1kgjYgWrBWyYSiPNhcL4EKA1gsz5cghnm7AMrOuASurM23yYVvb8A6Ge9GF1Tag48mT75kYFMcgQJr52NpdQwlRe_NAFZqdH4PNmUa9k-bR1b5bJ4d9klzvXr36fS8vbw6uzhdXLaaMI5bDTnnhhuhtsRCrfFWKS3EgDVXvda9tYxgDYcttoRhATXXpBOdpYSyDlOBT5qXs-9tineTyUWOLmvjvQomTlkiwRAWhFQQzaBOMedkrKwJxxpLIih_tS3_artqXhzMp-1ohj-KQ70VYDNw77zZ_99RLt4vlgLhKmxnocvF_PgtVOm7rLVwKj9_OJNf6RdOuhWVm8q_PfDBxjSqnVG-7HT9TnkTpxRqxf_I8RPCo6p9</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19613944</pqid></control><display><type>article</type><title>Influence of Parental SUD and ADHD on ADHD in their Offspring: Preliminary Results from a Pilot-controlled Family Study</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><source>Taylor & Francis:Master (3349 titles)</source><creator>Wilens, Timothy E. ; Hahesy, Amy L. ; Biederman, Joseph ; Bredin, Elizabeth ; Tanguay, Sarah ; Kwon, Anne ; Faraone, Stephen V.</creator><creatorcontrib>Wilens, Timothy E. ; Hahesy, Amy L. ; Biederman, Joseph ; Bredin, Elizabeth ; Tanguay, Sarah ; Kwon, Anne ; Faraone, Stephen V.</creatorcontrib><description>As part of a pilot-controlled family-based study of the children of parents with and without substance use disorders (SUD), the influence of parental SUD and ADHD on the risk for ADHD in offspring was evaluated. Using structured psychiatric interviews, 96 families (183 youth; mean age 11.6 years) were assessed. To evaluate the effect of parental ADHD and SUD, the offspring were stratified into four groups based on parental status: children of parents with neither ADHD nor SUD, children of parents with SUD only, children of parents with ADHD only, and children of parents with both ADHD and SUD. Using generalized estimating equation models, parental SUD and ADHD were used to predict ADHD in the offspring. The rate of children with ADHD increased among children of parents with neither disorder (3%), children of parents with SUD (13%), children of parents with ADHD (25%), and children of parents with both ADHD and SUD (50%) (p = .001). Children of parents with ADHD or ADHD plus SUD were more likely to have ADHD in comparison to children of parents with neither diagnosis (p < 0.05). Children of parents with ADHD plus SUD were at greater risk of ADHD in comparison to children of parents with SUD only (p = 0.01). Despite the small sample size, the results of this study seem to suggest that the offspring of SUD or ADHD parents are at elevated risk for ADHD compared to controls. The offspring of parents with both ADHD and SUD appear to be at the highest risk for ADHD, highlighting the need for careful screening of this group of youth for ADHD. Replication studies clarifying the nature and strength of the association are necessary.(Am J Addict 2005;14:179-187)</description><identifier>ISSN: 1055-0496</identifier><identifier>EISSN: 1521-0391</identifier><identifier>DOI: 10.1080/10550490590924872</identifier><identifier>PMID: 16019966</identifier><language>eng</language><publisher>Oxford, UK: Informa UK Ltd</publisher><subject>Attention Deficit Disorder with Hyperactivity - diagnosis ; Attention Deficit Disorder with Hyperactivity - epidemiology ; Attention Deficit Disorder with Hyperactivity - genetics ; Child ; Child of Impaired Parents ; Family ; Female ; Humans ; Male ; Pilot Projects ; Risk Factors ; Sex Factors ; Social Environment ; Substance-Related Disorders - diagnosis ; Substance-Related Disorders - epidemiology ; Substance-Related Disorders - genetics</subject><ispartof>The American journal on addictions, 2005-03, Vol.14 (2), p.179-187</ispartof><rights>2005 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2005</rights><rights>2005 American Academy of Addiction Psychiatry</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4673-c0777e7e9ab4f0cc3baac99d3c7a8cc8ff643c0db3f46390c7c4292f545623593</citedby><cites>FETCH-LOGICAL-c4673-c0777e7e9ab4f0cc3baac99d3c7a8cc8ff643c0db3f46390c7c4292f545623593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/10550490590924872$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/10550490590924872$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575,61221,61402</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16019966$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wilens, Timothy E.</creatorcontrib><creatorcontrib>Hahesy, Amy L.</creatorcontrib><creatorcontrib>Biederman, Joseph</creatorcontrib><creatorcontrib>Bredin, Elizabeth</creatorcontrib><creatorcontrib>Tanguay, Sarah</creatorcontrib><creatorcontrib>Kwon, Anne</creatorcontrib><creatorcontrib>Faraone, Stephen V.</creatorcontrib><title>Influence of Parental SUD and ADHD on ADHD in their Offspring: Preliminary Results from a Pilot-controlled Family Study</title><title>The American journal on addictions</title><addtitle>Am J Addict</addtitle><description>As part of a pilot-controlled family-based study of the children of parents with and without substance use disorders (SUD), the influence of parental SUD and ADHD on the risk for ADHD in offspring was evaluated. Using structured psychiatric interviews, 96 families (183 youth; mean age 11.6 years) were assessed. To evaluate the effect of parental ADHD and SUD, the offspring were stratified into four groups based on parental status: children of parents with neither ADHD nor SUD, children of parents with SUD only, children of parents with ADHD only, and children of parents with both ADHD and SUD. Using generalized estimating equation models, parental SUD and ADHD were used to predict ADHD in the offspring. The rate of children with ADHD increased among children of parents with neither disorder (3%), children of parents with SUD (13%), children of parents with ADHD (25%), and children of parents with both ADHD and SUD (50%) (p = .001). Children of parents with ADHD or ADHD plus SUD were more likely to have ADHD in comparison to children of parents with neither diagnosis (p < 0.05). Children of parents with ADHD plus SUD were at greater risk of ADHD in comparison to children of parents with SUD only (p = 0.01). Despite the small sample size, the results of this study seem to suggest that the offspring of SUD or ADHD parents are at elevated risk for ADHD compared to controls. The offspring of parents with both ADHD and SUD appear to be at the highest risk for ADHD, highlighting the need for careful screening of this group of youth for ADHD. Replication studies clarifying the nature and strength of the association are necessary.(Am J Addict 2005;14:179-187)</description><subject>Attention Deficit Disorder with Hyperactivity - diagnosis</subject><subject>Attention Deficit Disorder with Hyperactivity - epidemiology</subject><subject>Attention Deficit Disorder with Hyperactivity - genetics</subject><subject>Child</subject><subject>Child of Impaired Parents</subject><subject>Family</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Pilot Projects</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Social Environment</subject><subject>Substance-Related Disorders - diagnosis</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Substance-Related Disorders - genetics</subject><issn>1055-0496</issn><issn>1521-0391</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1uEzEUhUcIREvhAdggr9gN2OO_MayihrRFFY0IFYiN5Xhs4uKxW9ujkrfHaCJYIMHd3Cv5O0c6x03zHMFXCPbwNYKUQiIgFVB0pOfdg-YY0Q61EAv0sN71va0AO2qe5HwD6_SCPW6OEINICMaOm_uLYP1kgjYgWrBWyYSiPNhcL4EKA1gsz5cghnm7AMrOuASurM23yYVvb8A6Ge9GF1Tag48mT75kYFMcgQJr52NpdQwlRe_NAFZqdH4PNmUa9k-bR1b5bJ4d9klzvXr36fS8vbw6uzhdXLaaMI5bDTnnhhuhtsRCrfFWKS3EgDVXvda9tYxgDYcttoRhATXXpBOdpYSyDlOBT5qXs-9tineTyUWOLmvjvQomTlkiwRAWhFQQzaBOMedkrKwJxxpLIih_tS3_artqXhzMp-1ohj-KQ70VYDNw77zZ_99RLt4vlgLhKmxnocvF_PgtVOm7rLVwKj9_OJNf6RdOuhWVm8q_PfDBxjSqnVG-7HT9TnkTpxRqxf_I8RPCo6p9</recordid><startdate>200503</startdate><enddate>200503</enddate><creator>Wilens, Timothy E.</creator><creator>Hahesy, Amy L.</creator><creator>Biederman, Joseph</creator><creator>Bredin, Elizabeth</creator><creator>Tanguay, Sarah</creator><creator>Kwon, Anne</creator><creator>Faraone, Stephen V.</creator><general>Informa UK Ltd</general><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope></search><sort><creationdate>200503</creationdate><title>Influence of Parental SUD and ADHD on ADHD in their Offspring: Preliminary Results from a Pilot-controlled Family Study</title><author>Wilens, Timothy E. ; Hahesy, Amy L. ; Biederman, Joseph ; Bredin, Elizabeth ; Tanguay, Sarah ; Kwon, Anne ; Faraone, Stephen V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4673-c0777e7e9ab4f0cc3baac99d3c7a8cc8ff643c0db3f46390c7c4292f545623593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Attention Deficit Disorder with Hyperactivity - diagnosis</topic><topic>Attention Deficit Disorder with Hyperactivity - epidemiology</topic><topic>Attention Deficit Disorder with Hyperactivity - genetics</topic><topic>Child</topic><topic>Child of Impaired Parents</topic><topic>Family</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Pilot Projects</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Social Environment</topic><topic>Substance-Related Disorders - diagnosis</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Substance-Related Disorders - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilens, Timothy E.</creatorcontrib><creatorcontrib>Hahesy, Amy L.</creatorcontrib><creatorcontrib>Biederman, Joseph</creatorcontrib><creatorcontrib>Bredin, Elizabeth</creatorcontrib><creatorcontrib>Tanguay, Sarah</creatorcontrib><creatorcontrib>Kwon, Anne</creatorcontrib><creatorcontrib>Faraone, Stephen V.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>The American journal on addictions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilens, Timothy E.</au><au>Hahesy, Amy L.</au><au>Biederman, Joseph</au><au>Bredin, Elizabeth</au><au>Tanguay, Sarah</au><au>Kwon, Anne</au><au>Faraone, Stephen V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Parental SUD and ADHD on ADHD in their Offspring: Preliminary Results from a Pilot-controlled Family Study</atitle><jtitle>The American journal on addictions</jtitle><addtitle>Am J Addict</addtitle><date>2005-03</date><risdate>2005</risdate><volume>14</volume><issue>2</issue><spage>179</spage><epage>187</epage><pages>179-187</pages><issn>1055-0496</issn><eissn>1521-0391</eissn><abstract>As part of a pilot-controlled family-based study of the children of parents with and without substance use disorders (SUD), the influence of parental SUD and ADHD on the risk for ADHD in offspring was evaluated. Using structured psychiatric interviews, 96 families (183 youth; mean age 11.6 years) were assessed. To evaluate the effect of parental ADHD and SUD, the offspring were stratified into four groups based on parental status: children of parents with neither ADHD nor SUD, children of parents with SUD only, children of parents with ADHD only, and children of parents with both ADHD and SUD. Using generalized estimating equation models, parental SUD and ADHD were used to predict ADHD in the offspring. The rate of children with ADHD increased among children of parents with neither disorder (3%), children of parents with SUD (13%), children of parents with ADHD (25%), and children of parents with both ADHD and SUD (50%) (p = .001). Children of parents with ADHD or ADHD plus SUD were more likely to have ADHD in comparison to children of parents with neither diagnosis (p < 0.05). Children of parents with ADHD plus SUD were at greater risk of ADHD in comparison to children of parents with SUD only (p = 0.01). Despite the small sample size, the results of this study seem to suggest that the offspring of SUD or ADHD parents are at elevated risk for ADHD compared to controls. The offspring of parents with both ADHD and SUD appear to be at the highest risk for ADHD, highlighting the need for careful screening of this group of youth for ADHD. Replication studies clarifying the nature and strength of the association are necessary.(Am J Addict 2005;14:179-187)</abstract><cop>Oxford, UK</cop><pub>Informa UK Ltd</pub><pmid>16019966</pmid><doi>10.1080/10550490590924872</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1055-0496 |
| ispartof | The American journal on addictions, 2005-03, Vol.14 (2), p.179-187 |
| issn | 1055-0496 1521-0391 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_19613944 |
| source | MEDLINE; Access via Wiley Online Library; Taylor & Francis:Master (3349 titles) |
| subjects | Attention Deficit Disorder with Hyperactivity - diagnosis Attention Deficit Disorder with Hyperactivity - epidemiology Attention Deficit Disorder with Hyperactivity - genetics Child Child of Impaired Parents Family Female Humans Male Pilot Projects Risk Factors Sex Factors Social Environment Substance-Related Disorders - diagnosis Substance-Related Disorders - epidemiology Substance-Related Disorders - genetics |
| title | Influence of Parental SUD and ADHD on ADHD in their Offspring: Preliminary Results from a Pilot-controlled Family Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T10%3A08%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Influence%20of%20Parental%20SUD%20and%20ADHD%20on%20ADHD%20in%20their%20Offspring:%20Preliminary%20Results%20from%20a%20Pilot-controlled%20Family%20Study&rft.jtitle=The%20American%20journal%20on%20addictions&rft.au=Wilens,%20Timothy%20E.&rft.date=2005-03&rft.volume=14&rft.issue=2&rft.spage=179&rft.epage=187&rft.pages=179-187&rft.issn=1055-0496&rft.eissn=1521-0391&rft_id=info:doi/10.1080/10550490590924872&rft_dat=%3Cproquest_cross%3E19613944%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=19613944&rft_id=info:pmid/16019966&rfr_iscdi=true |