Kinetics of Releasable Synaptic Vesicles and Their Plastic Changes at Hippocampal Mossy Fiber Synapses

Hippocampal mossy fiber boutons (hMFBs) are presynaptic terminals displaying various forms of synaptic plasticity. The presynaptic mechanisms underlying synaptic plasticity still remain poorly understood. Here, we have combined high temporal resolution measurements of presynaptic capacitance and exc...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2017-12, Vol.96 (5), p.1033-1040.e3
Hauptverfasser:	Midorikawa, Mitsuharu, Sakaba, Takeshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Channels - physiology cAMP Cyclic AMP Cyclic AMP - physiology Excitatory postsynaptic potentials Excitatory Postsynaptic Potentials - physiology Exocytosis Hippocampus Kinetics Long-term potentiation Male Measurement techniques Mossy Fibers, Hippocampal - physiology Neuronal Plasticity - physiology Patch-Clamp Techniques Presynapse presynaptic Presynaptic plasticity protein kinase A Pyramidal Cells - physiology Rats Rats, Wistar Rodents Short term Spatial discrimination synapse Synapses Synapses - physiology Synaptic plasticity Synaptic Transmission Synaptic vesicles Synaptic Vesicles - physiology Temporal resolution Transmitters Vesicles
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