Lattice system of functionally distinct cell types in the neocortex

The mammalian neocortex contains many cell types, but whether they organize into repeated structures has been unclear. We discovered that major cell types in neocortical layer 5 form a lattice structure in many brain areas. Large-scale three-dimensional imaging revealed that distinct types of excita...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2017-11, Vol.358 (6363), p.610-615
Hauptverfasser:	Maruoka, Hisato, Nakagawa, Nao, Tsuruno, Shun, Sakai, Seiichiro, Yoneda, Taisuke, Hosoya, Toshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Clusters Dominance, Ocular Electrical junctions Electrical transmission Excitation Gap junctions Gap Junctions - physiology Gap Junctions - ultrastructure Hexagonal lattice Imaging, Three-Dimensional Mice Mice, Inbred C57BL Mice, Transgenic Modular systems Neocortex Neocortex - cytology Neocortex - physiology Neuroimaging Neurons Neurons - classification Neurons - cytology Neurons - physiology Ocular dominance Orientation behavior Projection Rodents Synapses - physiology Synapses - ultrastructure
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