Sub-chronic toxicity of low concentrations of industrial volatile organic pollutants in vitro

Organic solvents form an important class of pollutants in the ambient air and have been associated with neurotoxicity and immunotoxicity in humans. Here we investigated the biological effects of sub-chronic exposure to industrially important volatile organic solvents in vitro. Jurkat T cells were ex...

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Veröffentlicht in:	Toxicology and applied pharmacology 2007-02, Vol.219 (1), p.85-94
Hauptverfasser:	McDermott, Catherine, Allshire, Ashley, van Pelt, Frank N.A.M., Heffron, James J.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers Butanones - toxicity Calcium - metabolism Cell Line, Tumor Chemical and industrial products toxicology. Toxic occupational diseases Chromatography, Gas Cytotoxicity Environmental Pollutants - toxicity Glutathione - metabolism Hexanes - toxicity Homeostasis - drug effects Humans Industry Jurkat Cells L-Lactate Dehydrogenase - metabolism Medical sciences Methyl ethyl ketone Mitogen-Activated Protein Kinases - metabolism n-hexane No-Observed-Adverse-Effect Level Organic Chemicals - toxicity Organic solvents Oxidation-Reduction Phosphorylation Signal Transduction - drug effects Solvents Solvents - toxicity Toluene Toluene - toxicity Toxicology
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