Epitope Cross-Reactivity Frequently Differs between Central and Effector Memory HIV-Specific CD8 super(+) T Cells
HIV diversity may limit the breadth of vaccine coverage due to epitope sequence differences between strains. Although amino acid substitutions within CD8 super(+) T cell HIV epitopes can result in complete or partial abrogation of responses, this has primarily been demonstrated in effector CD8 super...
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Veröffentlicht in: | Journal of Immunology 2007-03, Vol.178 (6), p.3750-3756 |
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Sprache: | eng |
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