Epitope Cross-Reactivity Frequently Differs between Central and Effector Memory HIV-Specific CD8 super(+) T Cells

HIV diversity may limit the breadth of vaccine coverage due to epitope sequence differences between strains. Although amino acid substitutions within CD8 super(+) T cell HIV epitopes can result in complete or partial abrogation of responses, this has primarily been demonstrated in effector CD8 super...

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Veröffentlicht in:Journal of Immunology 2007-03, Vol.178 (6), p.3750-3756
Hauptverfasser: McKinnon, Lyle R, Ball, TBlake, Wachihi, Charles, McLaren, Paul J, Waruk, Jillian LM, Mao, Xiaojuan, Ramdahin, Sue, Anzala, AOmu, Kamene, Jane, Luo, Ma, Fowke, Keith R, Plummer, Francis A
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Sprache:eng
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