Mutant p53 Enhances Nuclear Factor κB Activation by Tumor Necrosis Factor α in Cancer Cells

Mutations in the p53 tumor suppressor are very frequent in human cancer. Often, such mutations lead to the constitutive overproduction of mutant p53 proteins, which may exert a cancer-promoting gain of function. We now report that cancer-associated mutant p53 can augment the induction of nuclear fac...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2007-03, Vol.67 (6), p.2396-2401
Hauptverfasser:	Weisz, Lilach, Damalas, Alexander, Liontos, Michalis, Karakaidos, Panagiotis, Fontemaggi, Giulia, Maor-Aloni, Revital, Kalis, Marina, Levrero, Massimo, Strano, Sabrina, Gorgoulis, Vassilis G., Rotter, Varda, Blandino, Giovanni, Oren, Moshe
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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