Restorative effect of insulin-like growth factor-l gene therapy in the hypothalamus of senile rats with dopaminergic dysfunction

Insulin-like growth factor-I (IGF-I) is emerging as a powerful neuroprotective molecule that is strongly induced in the central nervous system after different insults. We constructed a recombinant adenoviral vector (RAd-IGFI) harboring the gene for rat IGF-I and used it to implement IGF-I gene thera...

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Veröffentlicht in:	Gene therapy 2007-02, Vol.14 (3), p.237-245
Hauptverfasser:	Herenu, C B, Cristina, C, Rimoldi, O J, Becu-Villalobos, D, Cambiaggi, V, Portiansky, EL, Goya, R G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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