Optimizing therapy of seizures in patients with renal or hepatic dysfunction

Patients with epilepsy may suffer from renal or hepatic diseases that interfere with their antiepileptic drug (AED) treatment. Furthermore, such diseases may themselves cause seizures. Reduced renal function and hypoalbuminemia lead to accumulation of renally excreted AEDs, such as gabapentin, vigab...

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Veröffentlicht in:	Neurology 2006-12, Vol.67 (12 Suppl 4), p.S28-S33
Hauptverfasser:	Lacerda, Glenda, Krummel, Thierry, Sabourdy, Cécile, Ryvlin, Philippe, Hirsch, Edouard
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - metabolism Anticonvulsants - pharmacokinetics Anticonvulsants - therapeutic use Epilepsy - complications Epilepsy - drug therapy Epilepsy - etiology Epilepsy - metabolism Humans Kidney Diseases - complications Kidney Diseases - metabolism Kidney Diseases - therapy Liver Diseases - complications Liver Diseases - metabolism Renal Dialysis
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