Liver Genes Expression Induced by Tamoxifen Loaded Solid Lipid Nanoparticles in Wistar Female Rats

The objective of this study was to investigate the effect of free tamoxifen and tamoxifen-loaded solid lipid nanoparticles (SLN) on cytochrome P450 (CYP3A2) and flavin-containing monooxygenase1 (FMO1) genes expression in the liver of female Wistar rats. Thirty female Wistar rats aged 7–8 weeks, were...

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Veröffentlicht in:	Cell biochemistry and biophysics 2018-06, Vol.76 (1-2), p.303-310
Hauptverfasser:	Zanganeh, Naser, Ziamajidi, Nasrin, Khodadadi, Iraj, Saidijam, Massoud, Abbasalipourkabir, Roghayeh
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Biotechnology Body weight Cell Biology Cytochrome P450 Dimethylaniline monooxygenase (N-oxide-forming) Dispersion Flavin Gene expression Genes Life Sciences Lipids Liver Nanoparticles Oils & fats Olive oil Original Paper Ovariectomy Pharmacology/Toxicology Rats Rodents Tamoxifen
Online-Zugang:	Volltext
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