Fragment-to-Lead Medicinal Chemistry Publications in 2016

Fragment-to-Lead Medicinal Chemistry Publications in 2016

The popularity of fragment-based drug discovery (FBDD) is demonstrated by the number of recent successful fragment-to-lead (F2L) publications. This Miniperspective provides a tabulated summary of the F2L literature published in the year 2016, along with discussion of general trends. It uses the same...

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Veröffentlicht in:Journal of medicinal chemistry 2018-03, Vol.61 (5), p.1774-1784
Hauptverfasser: Johnson, Christopher N, Erlanson, Daniel A, Jahnke, Wolfgang, Mortenson, Paul N, Rees, David C
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Sprache:eng
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Chemistry, Pharmaceutical - trends
Drug Discovery - methods
Small Molecule Libraries
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container_end_page 1784
container_issue 5
container_start_page 1774
container_title Journal of medicinal chemistry
container_volume 61
creator Johnson, Christopher N
Erlanson, Daniel A
Jahnke, Wolfgang
Mortenson, Paul N
Rees, David C
description The popularity of fragment-based drug discovery (FBDD) is demonstrated by the number of recent successful fragment-to-lead (F2L) publications. This Miniperspective provides a tabulated summary of the F2L literature published in the year 2016, along with discussion of general trends. It uses the same format as our summary of the 2015 literature and is intended to be a resource for both FBDD practitioners and medicinal chemists in general.
doi_str_mv 10.1021/acs.jmedchem.7b01298
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subjects Chemistry, Pharmaceutical - trends
Drug Discovery - methods
Small Molecule Libraries
title Fragment-to-Lead Medicinal Chemistry Publications in 2016
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