The antinociceptive efficacy of morphine, metamizol, or their combination in an experimental rat model with different levels of inflammatory pain

The purpose of this work was to evaluate the antinociceptive efficacy of an optimal morphine and metamizol combination on different levels of nociception (levels I, II, and III) using the “Pain-induced functional impairment model in the rat”. The effect of acetylsalicylic acid was examined as a refe...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2008-11, Vol.91 (1), p.196-201
Hauptverfasser:	LOPEZMUNOZ, F, GODINEZCHAPARRO, B, HUERTACRUZ, J, GUEVARALOPEZ, U, DOMINGUEZRAMIREZ, A, CORTESARROYO, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - therapeutic use Animals Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Aspirin - therapeutic use Biological and medical sciences Dipyrone - therapeutic use Dose-Response Relationship, Drug Drug Synergism Drug Therapy, Combination Inflammation - chemically induced Inflammation - complications Male Medical sciences Metamizol Morphine Morphine - therapeutic use Nociception Pain Pain - chemically induced Pain - drug therapy Pain - etiology Pain Measurement - drug effects PIFIR model Rats Rats, Wistar Synergism Uric Acid
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