PD-1:PD-L1 Interactions Contribute to the Functional Suppression of Virus-Specific CD8 super(+) T Lymphocytes in the Liver

Mechanisms contributing to the development of chronic viral infections, including chronic hepatitis B virus (HBV) infections, are not well understood. We have shown recently that production of IFN- gamma , an important antiviral cytokine, by HBV-specific CTLs is rapidly induced when they enter the l...

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Veröffentlicht in:	Journal of Immunology 2007-03, Vol.178 (5), p.2714-2720
Hauptverfasser:	Maier, Holly, Isogawa, Masanori, Freeman, Gordon J, Chisari, Francis V
Format:	Artikel
Sprache:	eng
Schlagworte:	Hepatitis B virus
Online-Zugang:	Volltext
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