One‐Pot Synthesis of Cyclopropane‐Fused Cyclic Amidines: An Oxidative Carbanion Cyclization

A novel and efficient one‐pot method has been developed for the synthesis of cyclopropane‐fused bicyclic amidines on the basis of a CuBr2‐mediated oxidative cyclization of carbanions. The usefulness of this unique multicomponent strategy has been demonstrated by the use of a wide variety of substrat...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-12, Vol.56 (51), p.16197-16201
Hauptverfasser:	Veeranna, Kirana Devarahosahalli, Das, Kanak Kanti, Baskaran, Sundarababu
Format:	Artikel
Sprache:	eng
Schlagworte:	3-azabicyclo[n.1.0]alkanes Alkanes Biological activity cyclic amidines Cyclopropane Intermediates ketenimines SET oxidative cyclization Substrates Synthesis synthetic methods
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