Guanine Nitration in Idiopathic Pulmonary Fibrosis and Its Implication for Carcinogenesis

Nitric oxide (NO)-induced nitrative stress of nucleic acids, as evidenced by guanine nitration, appears to be involved in inflammation-induced carcinogenesis. A high incidence of lung cancer in idiopathic pulmonary fibrosis (IPF) is the major reason for poor prognosis in patients with IPF. We immuno...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2006-09, Vol.174 (6), p.665-673
Hauptverfasser: Terasaki, Yasuhiro, Akuta, Teruo, Terasaki, Mika, Sawa, Tomohiro, Mori, Takeshi, Okamoto, Tatsuya, Ozaki, Masakazu, Takeya, Motohiro, Akaike, Takaaki
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Sprache:eng
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