Stigmasterol inhibits lipopolysaccharide-induced innate immune responses in murine models

Stigmasterol is a naturally occurring steroid alcohol which occurs in vegetables, soya and a large variety of medicinal plants. Stigmasterol and other phytosterols have been documented as immunomodulators with huge therapeutic potential. We assessed the mitigating effect of stigmasterol on non-fatal...

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Veröffentlicht in:	International immunopharmacology 2017-12, Vol.53, p.105-113
Hauptverfasser:	Antwi, Aaron O., Obiri, David D., Osafo, Newman, Forkuo, Arnold D., Essel, Leslie B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Alanine transaminase Alanine Transaminase - blood Alcohols Animal models Animals Aspartate transaminase Cell proliferation Cell Proliferation - drug effects Cells, Cultured Disease control Disease Models, Animal Female Fever Fever - chemically induced Fever - drug therapy Histopathology Humans Immune response Immunity, Innate Immunomodulation Immunomodulators Inflammation Inflammation - chemically induced Inflammation - drug therapy Injections, Intraperitoneal Innate immunity Lipopolysaccharide-induced Lipopolysaccharides Lipopolysaccharides - administration & dosage Liver Lung - drug effects Lung - pathology Lungs Male Medicinal plants Mice Mice, Inbred C57BL Mortality Neutrophils - immunology Peritoneal fluid Peritoneum Phytosterols Plants (botany) Polyethylene glycol Rats Rats, Wistar Serum levels Sterols Stigmasterol Transaminase Vegetables
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