Activation of non-canonical NF-κB pathway mediated by STP-A11, an oncoprotein of Herpesvirus saimiri

Abstract Although Saimiri Transforming Protein (STP)-A11, an oncoprotein of Herpesvirus saimiri , has been known to activate NF-κB signaling pathway, the detailed mechanism has not been reported yet. We herein report that STP-A11 activates non-canonical NF-κB pathway, resulting in p100 processing to...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2007-03, Vol.359 (1), p.37-45
Hauptverfasser:	Cho, Il-Rae, Jeong, Sunam, Jhun, Byung Hak, An, Won G, Lee, BokSoo, Kwak, Youn-Tae, Lee, Sun-Hwa, Jung, Jae U, Chung, Young-Hwa
Format:	Artikel
Sprache:	eng
Schlagworte:	Canonical NF-κB Herpesvirus saimiri IKK Infectious Disease NF-κB2 NIK Non-canonical NF-κB p100 processing p52 protein STP-A11
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