TGF‐β pro‐oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway

Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming growth factor β1 (TGF‐β) signaling pathways play critical roles in controlling these cell fate decisions. TGF‐β has been previously shown to exer...

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Veröffentlicht in:	Glia 2018-02, Vol.66 (2), p.396-412
Hauptverfasser:	Gómez Pinto, Laura I., Rodríguez, Debora, Adamo, Ana M., Mathieu, Patricia A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Cells, Cultured cytokine Humans Jagged1 ligand Lateral Ventricles - cytology Lateral Ventricles - drug effects Lateral Ventricles - metabolism neural progenitor cell Neural Stem Cells - drug effects Neural Stem Cells - metabolism oligodendrocytes Oligodendroglia - drug effects Oligodendroglia - metabolism Rats Rats, Wistar Receptors, Notch - metabolism Signal Transduction - drug effects Signal Transduction - physiology Transforming Growth Factor beta1 - pharmacology
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