Oncolytic reovirus therapy: Pilot study in dogs with spontaneously occurring tumours

Oncolytic virotherapy is a novel treatment involving replication‐competent virus in the elimination of cancer. We have previously reported the oncolytic effects of reovirus in various canine cancer cell lines. This study aims to establish the safety profile of reovirus in dogs with spontaneously occ...

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Veröffentlicht in:	Veterinary & comparative oncology 2018-06, Vol.16 (2), p.229-238
Hauptverfasser:	Hwang, C. C., Igase, M., Sakurai, M., Haraguchi, T., Tani, K., Itamoto, K., Shimokawa, T., Nakaichi, M., Nemoto, Y., Noguchi, S., Coffey, M., Okuda, M., Mizuno, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Neutralizing - blood Antineoplastic Agents - immunology Antineoplastic Agents - pharmacology canine Dog Diseases - drug therapy Dog Diseases - immunology Dogs dosing regimen Female Japan Male Neoplasms - drug therapy Neoplasms - immunology Neoplasms - veterinary oncolytic virotherapy Oncolytic Virotherapy - methods Oncolytic Virotherapy - veterinary Oncolytic Viruses - immunology Pilot Projects Polymerase Chain Reaction Reoviridae - immunology reovirus safety profile Schools, Veterinary Treatment Outcome tumour Virus Shedding
Online-Zugang:	Volltext
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