beta -PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrP super(Sc)

Prion diseases are associated with accumulation of strain-dependent biochemically distinct, disease-related isoforms (PrP super(Sc)) of host-encoded prion protein (PrP super(C)). PrP super(Sc) is characterised by increased beta -sheet content, detergent insolubility and protease resistance. Recombin...

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Veröffentlicht in:Biochimica et biophysica acta. Proteins and proteomics 2007-11, Vol.1774 (11), p.1438-1450
Hauptverfasser: Khalili-Shirazi, Azadeh, Kaisar, Maria, Mallinson, Gary, Jones, Samantha, Bhelt, Daljit, Fraser, Carol, Clarke, Anthony R, Hawke, Simon H, Jackson, Graham S, Collinge, John
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Sprache:eng
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