Impact of age on cardiovascular function, inflammation, and oxidative stress in experimental asphyxial cardiac arrest

Background Advanced age is an independent predictor of poor outcome after cardiac arrest (CA). From experimental studies of regional ischemia‐reperfusion injury, advanced age is associated with larger infarct size, reduced organ function, and augmented oxidative stress. The objective of this study w...

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Veröffentlicht in:	Acta anaesthesiologica Scandinavica 2018-01, Vol.62 (1), p.49-62
Hauptverfasser:	Secher, N., Østergaard, L., Tønnesen, E., Hansen, F. B., Granfeldt, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Age Age Factors Animals Asphyxia Asphyxia - physiopathology Blood Pressure Brain Carbonyls Cardiovascular system Cerebral blood flow Elastase Endothelium, Vascular - physiology Heart Heart Arrest - physiopathology Heart diseases Heme Oxygenase (Decyclizing) - blood Inflammation - etiology Injury prevention Interleukin 1 Interleukin 10 Interleukin 6 Interleukin-6 - blood Ischemia Kidneys Lungs Male Oxidative Stress Plasma levels Rats Rats, Sprague-Dawley Reperfusion Rodents Tumor necrosis factor Ventricle
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