Moderator's view: High-volume plasma exchange: pro, con and consensus

Moderator's view: High-volume plasma exchange: pro, con and consensus

I have been asked to comment on the pro and con opinions regarding high-volume plasma exchange. The authors of both positions have provided cogent arguments and a reasonable approach to choosing the exchange volume for any given therapeutic plasma exchange. The major issue of relevance in this discu...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 2017-09, Vol.32 (9), p.1464-1467
1. Verfasser: Kaplan, Andre A
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Sprache:eng
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Humans
Plasma Exchange - methods
Plasma Exchange - standards
Plasmapheresis - methods
Plasmapheresis - standards
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creator Kaplan, Andre A
description I have been asked to comment on the pro and con opinions regarding high-volume plasma exchange. The authors of both positions have provided cogent arguments and a reasonable approach to choosing the exchange volume for any given therapeutic plasma exchange. The major issue of relevance in this discussion is the nature of the toxins targeted for removal. These parameters include molecular weight, the apparent volume of distribution, the degree of protein binding, the biologic and chemical half-life, and the severity and rapidity of its toxicity.
doi_str_mv 10.1093/ndt/gfx091
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source MEDLINE; Oxford Journals Online; Alma/SFX Local Collection; EZB Electronic Journals Library
subjects Humans
Plasma Exchange - methods
Plasma Exchange - standards
Plasmapheresis - methods
Plasmapheresis - standards
title Moderator's view: High-volume plasma exchange: pro, con and consensus
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