Linarin suppresses glioma through inhibition of NF-κB/p65 and up-regulating p53 expression in vitro and in vivo

Glioma is the most common form of malignant brain cancer with high mortality rate in human. Therefore, finding effective therapeutic strategy and revealing the underlying molecular mechanism is necessary. Plant-extracted flavonoid glycosides have been suggested to be bioactive compounds with pleiotr...

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Veröffentlicht in:Biomedicine & pharmacotherapy 2017-11, Vol.95, p.363-374
Hauptverfasser: Zhen, Zi-Gang, Ren, Shao-Hua, Ji, Hong-Ming, Ma, Jiu-Hong, Ding, Xin-Min, Feng, Fu-Qiang, Chen, Shing-Li, Zou, Peng, Ren, Jin-Rui, Jia, Lu
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