Identification of atractyloside by LC–ESI–MS in alleged herbal poisonings

An LC–MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa, Callilepis laureola, in biological matrices such as body fluids and human viscera.

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Veröffentlicht in:Forensic science international 2006-11, Vol.163 (1), p.81-92
Hauptverfasser: Steenkamp, P.A., Harding, N.M., van Heerden, F.R., van Wyk, B.-E.
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container_title Forensic science international
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creator Steenkamp, P.A.
Harding, N.M.
van Heerden, F.R.
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description An LC–MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa, Callilepis laureola, in biological matrices such as body fluids and human viscera.
doi_str_mv 10.1016/j.forsciint.2005.11.010
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subjects Asteraceae
Atractylodes
Atractyloside
Atractyloside - analysis
Atractyloside - poisoning
Biological and medical sciences
Body Fluids - chemistry
Callilepis - chemistry
Callilepis - poisoning
Callilepis laureola
Carboxyatractyloside
Chemistry, Forensic
Chromatography
Chromatography, Liquid
Forensic chemistry
Forensic medicine
Forensic Pathology
Forensic sciences
General aspects
Herbal medicine
High performance liquid chromatography
HPLC
Humans
Identification and classification
Investigative techniques, diagnostic techniques (general aspects)
LC–MS
Mass spectrometry
Medical sciences
Methods
Plant Extracts - chemistry
Plant Extracts - poisoning
Plant Poisoning - diagnosis
Plant Poisoning - pathology
Plant Roots - chemistry
Poisoning
Public health. Hygiene
Public health. Hygiene-occupational medicine
Spectrometry, Mass, Electrospray Ionization
Studies
Viscera - chemistry
title Identification of atractyloside by LC–ESI–MS in alleged herbal poisonings
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