Identification of atractyloside by LC–ESI–MS in alleged herbal poisonings
An LC–MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa, Callilepis laureola, in biological matrices such as body fluids and human viscera.
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Veröffentlicht in: | Forensic science international 2006-11, Vol.163 (1), p.81-92 |
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creator | Steenkamp, P.A. Harding, N.M. van Heerden, F.R. van Wyk, B.-E. |
description | An LC–MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa,
Callilepis laureola, in biological matrices such as body fluids and human viscera. |
doi_str_mv | 10.1016/j.forsciint.2005.11.010 |
format | Article |
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Callilepis laureola, in biological matrices such as body fluids and human viscera.</description><identifier>ISSN: 0379-0738</identifier><identifier>EISSN: 1872-6283</identifier><identifier>DOI: 10.1016/j.forsciint.2005.11.010</identifier><identifier>PMID: 16376039</identifier><identifier>CODEN: FSINDR</identifier><language>eng</language><publisher>Kidlington: Elsevier Ireland Ltd</publisher><subject>Asteraceae ; Atractylodes ; Atractyloside ; Atractyloside - analysis ; Atractyloside - poisoning ; Biological and medical sciences ; Body Fluids - chemistry ; Callilepis - chemistry ; Callilepis - poisoning ; Callilepis laureola ; Carboxyatractyloside ; Chemistry, Forensic ; Chromatography ; Chromatography, Liquid ; Forensic chemistry ; Forensic medicine ; Forensic Pathology ; Forensic sciences ; General aspects ; Herbal medicine ; High performance liquid chromatography ; HPLC ; Humans ; Identification and classification ; Investigative techniques, diagnostic techniques (general aspects) ; LC–MS ; Mass spectrometry ; Medical sciences ; Methods ; Plant Extracts - chemistry ; Plant Extracts - poisoning ; Plant Poisoning - diagnosis ; Plant Poisoning - pathology ; Plant Roots - chemistry ; Poisoning ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Spectrometry, Mass, Electrospray Ionization ; Studies ; Viscera - chemistry</subject><ispartof>Forensic science international, 2006-11, Vol.163 (1), p.81-92</ispartof><rights>2005 Elsevier Ireland Ltd</rights><rights>2006 INIST-CNRS</rights><rights>COPYRIGHT 2006 The Lancet Publishing Group, a division of Elsevier Science Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c563t-4a3aaff2af9fd741a7abdaa834b60ebb2ec33237c2d711769600ca9d726f0a083</citedby><cites>FETCH-LOGICAL-c563t-4a3aaff2af9fd741a7abdaa834b60ebb2ec33237c2d711769600ca9d726f0a083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1033832860?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18207101$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16376039$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Steenkamp, P.A.</creatorcontrib><creatorcontrib>Harding, N.M.</creatorcontrib><creatorcontrib>van Heerden, F.R.</creatorcontrib><creatorcontrib>van Wyk, B.-E.</creatorcontrib><title>Identification of atractyloside by LC–ESI–MS in alleged herbal poisonings</title><title>Forensic science international</title><addtitle>Forensic Sci Int</addtitle><description>An LC–MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa,
Callilepis laureola, in biological matrices such as body fluids and human viscera.</description><subject>Asteraceae</subject><subject>Atractylodes</subject><subject>Atractyloside</subject><subject>Atractyloside - analysis</subject><subject>Atractyloside - poisoning</subject><subject>Biological and medical sciences</subject><subject>Body Fluids - chemistry</subject><subject>Callilepis - chemistry</subject><subject>Callilepis - poisoning</subject><subject>Callilepis laureola</subject><subject>Carboxyatractyloside</subject><subject>Chemistry, Forensic</subject><subject>Chromatography</subject><subject>Chromatography, Liquid</subject><subject>Forensic chemistry</subject><subject>Forensic medicine</subject><subject>Forensic Pathology</subject><subject>Forensic sciences</subject><subject>General aspects</subject><subject>Herbal medicine</subject><subject>High performance liquid chromatography</subject><subject>HPLC</subject><subject>Humans</subject><subject>Identification and classification</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>LC–MS</subject><subject>Mass spectrometry</subject><subject>Medical sciences</subject><subject>Methods</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - poisoning</subject><subject>Plant Poisoning - diagnosis</subject><subject>Plant Poisoning - pathology</subject><subject>Plant Roots - chemistry</subject><subject>Poisoning</subject><subject>Public health. Hygiene</subject><subject>Public health. 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Callilepis laureola, in biological matrices such as body fluids and human viscera.</abstract><cop>Kidlington</cop><pub>Elsevier Ireland Ltd</pub><pmid>16376039</pmid><doi>10.1016/j.forsciint.2005.11.010</doi><tpages>12</tpages></addata></record> |
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subjects | Asteraceae Atractylodes Atractyloside Atractyloside - analysis Atractyloside - poisoning Biological and medical sciences Body Fluids - chemistry Callilepis - chemistry Callilepis - poisoning Callilepis laureola Carboxyatractyloside Chemistry, Forensic Chromatography Chromatography, Liquid Forensic chemistry Forensic medicine Forensic Pathology Forensic sciences General aspects Herbal medicine High performance liquid chromatography HPLC Humans Identification and classification Investigative techniques, diagnostic techniques (general aspects) LC–MS Mass spectrometry Medical sciences Methods Plant Extracts - chemistry Plant Extracts - poisoning Plant Poisoning - diagnosis Plant Poisoning - pathology Plant Roots - chemistry Poisoning Public health. Hygiene Public health. Hygiene-occupational medicine Spectrometry, Mass, Electrospray Ionization Studies Viscera - chemistry |
title | Identification of atractyloside by LC–ESI–MS in alleged herbal poisonings |
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