Sucrosomial® iron absorption studied by in vitro and ex-vivo models

This paper presents a comparative evaluation of different oral ferric iron formulations for ability to retain Fe3+ in simulated gastric fluid (SGF), be internalized by cells lining intestinal epithelium, and cross it to reach the bloodstream. In all formulations iron was ferric pyrophosphate, the ex...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2018-01, Vol.111, p.425-431
Hauptverfasser:	Fabiano, Angela, Brilli, Elisa, Fogli, Stefano, Beconcini, Denise, Carpi, Sara, Tarantino, Germano, Zambito, Ylenia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Body Fluids Caco-2 Cells Diphosphates - chemistry Diphosphates - metabolism Dosage Forms Drug Liberation Humans Intestines - metabolism Iron - chemistry Iron - metabolism Iron absorption Lechitin, Sideral Lecithins Nano-sized structures Phospholipids Rats Sucrester Sucrose - chemistry
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