Label‐free imaging of redox status and collagen deposition showing metabolic differences in the heart

The heart has high metabolic demand to maintain function. The primary source of energy supply to support correct contractile muscle function differs between a fetus and an adult. In fetal life, ATP is primarily generated by glycolysis and lactate oxidation, whereas following birth, there is a shift...

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Veröffentlicht in:	Journal of biophotonics 2018-03, Vol.11 (3), p.n/a
Hauptverfasser:	Morrison, Janna L., Sorvina, Alexandra, Darby, Jack R.T., Bader, Christie A., Lock, Mitchell C., Seed, Mike, Kuchel, Tim, Plush, Sally E., Brooks, Douglas A.
Format:	Artikel
Sprache:	eng
Schlagworte:	2‐photon excitation fluorescence microscopy cardiomyocyte Cofactors Collagen Deposition Excitation Fatty acids Fetuses Flavin-adenine dinucleotide Fluorescence Fluorescence microscopy Glycolysis Growth patterns Heart Heart diseases Imaging Lactic acid metabolic activity Metabolism Microscopy Mitochondria Muscle contraction Muscles NAD Nicotinamide Nicotinamide adenine dinucleotide Oxidation Oxygenation proliferation quiescent/hypertrophic Skeletal muscle Technology
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