Antidepressant‐Induced Inhibition of Genital Vascular Responses Is Reversed by Vardenafil in Female Rabbits

Administration of serotonin reuptake inhibitors (SRI) or serotonin and norepinephrine reuptake inhibitors (SNRI) relieves depressive symptoms but may cause sexual dysfunction in women and men. The aim of the present study was to evaluate the effects of the phosphodiesterase type 5 (PDE5) inhibitor,...

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Veröffentlicht in:	Journal of sexual medicine 2006-11, Vol.3 (6), p.988-995
Hauptverfasser:	Angulo, Javier, Cuevas, Pedro, Cuevas, Begona, Bischoff, Erwin, De Tejada, Iñigo Saenz
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressant Antidepressive Agents - adverse effects Blood Vessels - drug effects Duloxetine Electric Stimulation Female Female Sexual Dysfunction Genital Vascular Responses Imidazoles - administration & dosage Imidazoles - pharmacology Laser-Doppler Flowmetry Nitric Oxide Paroxetine Phosphodiesterase Inhibitors - administration & dosage Phosphodiesterase Inhibitors - pharmacology Phosphodiesterase Type 5 Piperazines - administration & dosage Piperazines - pharmacology Rabbits Regional Blood Flow - drug effects Sexual Dysfunction, Physiological - drug therapy Sexual Dysfunction, Physiological - etiology Sulfones - administration & dosage Sulfones - pharmacology Triazines - administration & dosage Triazines - pharmacology Vagina - blood supply Vagina - drug effects Vardenafil Vardenafil Dihydrochloride Vasodilation - drug effects Vasodilator Agents - administration & dosage Vasodilator Agents - pharmacology Venlafaxine
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