Mechanisms driving the ageing heart

Cardiovascular disease (CVD) is the leading cause of death globally. One of the main risk factors for CVD is age, however the biological processes that occur in the heart during ageing are poorly understood. It is therefore important to understand the fundamental mechanisms driving heart ageing to e...

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Veröffentlicht in:	Experimental gerontology 2018-08, Vol.109, p.5-15
Hauptverfasser:	Anderson, Rhys, Richardson, Gavin D., Passos, João F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Cardiovascular Diseases - etiology Cellular Senescence - physiology DNA Damage DNA damage response DNA Repair Heart - physiology Humans Mitochondria Mitochondria - physiology Reactive oxygen species Reactive Oxygen Species - metabolism Senescence Telomere Telomeres
Online-Zugang:	Volltext
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