Sequential one-pot multienzyme synthesis of hyaluronan and its derivative

•A sequential one-pot multienzyme synthetic strategy was developed which combined in situ sugar nucleotides generation with HA polymerization.•Partial labeled HA derivative was synthesized by metabolic incorporation of monosaccharide analogues into the sequential OPME system.•Cross-linked HA hydroge...

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Veröffentlicht in:	Carbohydrate polymers 2017-12, Vol.178, p.221-227
Hauptverfasser:	Li, Shuang, Wang, Shuaishuai, Fu, Xuan, Liu, Xian-wei, Wang, Peng George, Fang, Junqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Cross-linked hydrogel Hyaluronan Hyaluronan derivative One-pot multienzyme Sugar nucleotide
Online-Zugang:	Volltext
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