Convolvulus pluricaulis (Shankhapushpi) ameliorates human microtubule-associated protein tau (hMAPτ) induced neurotoxicity in Alzheimer’s disease Drosophila model

•First study on ameliorative effects of Convolvulus pluricaulis root extract on neurotoxicity in Alzheimer’s disease Drosophila model.•C. pluricaulis markedly improves hMAPτ induced locomotor deficits in tauopathy flies.•C. pluricaulis significantly offsets hMAPτ induced early death and extends the...

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Veröffentlicht in:	Journal of chemical neuroanatomy 2019-01, Vol.95, p.115-122
Hauptverfasser:	Kizhakke P., Anupama, Olakkaran, Shilpa, Antony, Anet, Tilagul K., Siddanna, Hunasanahally P., Gurushankara
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - pathology Alzheimer’s disease Animals Convolvulus Convolvulus pluricaulis Disease Models, Animal Drosophila melanogaster Humans Lifespan Materia Medica - pharmacology Medhya rasayana Neuroprotective Agents - pharmacology Oxidative stress Oxidative Stress - drug effects Plant Extracts - pharmacology Shankhapushpi tau Proteins - genetics tau Proteins - toxicity Tauopathies - pathology Tauopathy model
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