Association of Chronic Kidney Disease With In-Hospital Outcomes of Transcatheter Aortic Valve Replacement
This study sought to determine the association of chronic kidney disease (CKD) with in-hospital outcomes of transcatheter aortic valve replacement (TAVR). CKD is a known independent risk factor for worse outcomes after surgical aortic valve replacement (SAVR). However, data on outcomes of patients w...
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| Veröffentlicht in: | JACC. Cardiovascular interventions 2017-10, Vol.10 (20), p.2050-2060 |
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| creator | Gupta, Tanush Goel, Kashish Kolte, Dhaval Khera, Sahil Villablanca, Pedro A. Aronow, Wilbert S. Bortnick, Anna E. Slovut, David P. Taub, Cynthia C. Kizer, Jorge R. Pyo, Robert T. Abbott, J. Dawn Fonarow, Gregg C. Rihal, Charanjit S. Garcia, Mario J. Bhatt, Deepak L. |
| description | This study sought to determine the association of chronic kidney disease (CKD) with in-hospital outcomes of transcatheter aortic valve replacement (TAVR).
CKD is a known independent risk factor for worse outcomes after surgical aortic valve replacement (SAVR). However, data on outcomes of patients with CKD undergoing TAVR are limited, especially in those on chronic dialysis.
The authors used data from the 2012 to 2014 National Inpatient Sample database to identify all patients ≥18 years of age who underwent TAVR. International Classification of Diseases-Ninth Revision-Clinical Modification codes were used to identify patients with no CKD, CKD (without chronic dialysis), or end-stage renal disease (ESRD) on long-term dialysis. Multivariable logistic regression models were constructed using generalized estimating equations to examine in-hospital outcomes.
Of 41,025 patients undergoing TAVR from 2012 to 2014, 25,585 (62.4%) had no CKD, 13,750 (33.5%) had CKD, and 1,690 (4.1%) had ESRD. Compared with patients with no CKD, in-hospital mortality was significantly higher in patients with CKD or ESRD (3.8% vs. 4.5% vs. 8.3%; adjusted odds ratio [no CKD as reference]: 1.39 [95% confidence interval: 1.24 to 1.55] for CKD and 2.58 [95% confidence interval: 2.09 to 3.13] for ESRD). Patients with CKD or ESRD had a higher incidence of major adverse cardiovascular events (composite of death, myocardial infarction, or stroke), net adverse cardiovascular events (composite of major adverse cardiovascular events, major bleeding, or vascular complications), and pacemaker implantation compared with patients without CKD. Acute kidney injury (AKI) and AKI requiring dialysis were associated with several-fold higher risk-adjusted in-hospital mortality in patients in the no CKD and CKD groups. Moreover, the incidence of AKI and AKI requiring dialysis did not decline during the study period.
Patients with CKD or ESRD have worse in-hospital outcomes after TAVR. AKI is associated with higher in-hospital mortality in patients undergoing TAVR and the incidence of AKI has not declined over the years.
[Display omitted] |
| doi_str_mv | 10.1016/j.jcin.2017.07.044 |
| format | Article |
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CKD is a known independent risk factor for worse outcomes after surgical aortic valve replacement (SAVR). However, data on outcomes of patients with CKD undergoing TAVR are limited, especially in those on chronic dialysis.
The authors used data from the 2012 to 2014 National Inpatient Sample database to identify all patients ≥18 years of age who underwent TAVR. International Classification of Diseases-Ninth Revision-Clinical Modification codes were used to identify patients with no CKD, CKD (without chronic dialysis), or end-stage renal disease (ESRD) on long-term dialysis. Multivariable logistic regression models were constructed using generalized estimating equations to examine in-hospital outcomes.
Of 41,025 patients undergoing TAVR from 2012 to 2014, 25,585 (62.4%) had no CKD, 13,750 (33.5%) had CKD, and 1,690 (4.1%) had ESRD. Compared with patients with no CKD, in-hospital mortality was significantly higher in patients with CKD or ESRD (3.8% vs. 4.5% vs. 8.3%; adjusted odds ratio [no CKD as reference]: 1.39 [95% confidence interval: 1.24 to 1.55] for CKD and 2.58 [95% confidence interval: 2.09 to 3.13] for ESRD). Patients with CKD or ESRD had a higher incidence of major adverse cardiovascular events (composite of death, myocardial infarction, or stroke), net adverse cardiovascular events (composite of major adverse cardiovascular events, major bleeding, or vascular complications), and pacemaker implantation compared with patients without CKD. Acute kidney injury (AKI) and AKI requiring dialysis were associated with several-fold higher risk-adjusted in-hospital mortality in patients in the no CKD and CKD groups. Moreover, the incidence of AKI and AKI requiring dialysis did not decline during the study period.
Patients with CKD or ESRD have worse in-hospital outcomes after TAVR. AKI is associated with higher in-hospital mortality in patients undergoing TAVR and the incidence of AKI has not declined over the years.
[Display omitted]</description><identifier>ISSN: 1936-8798</identifier><identifier>EISSN: 1876-7605</identifier><identifier>DOI: 10.1016/j.jcin.2017.07.044</identifier><identifier>PMID: 29050621</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>acute kidney injury ; Acute Kidney Injury - mortality ; Acute Kidney Injury - physiopathology ; Acute Kidney Injury - therapy ; Aged ; Aged, 80 and over ; Aortic Valve - diagnostic imaging ; Aortic Valve - physiopathology ; Aortic Valve - surgery ; Aortic Valve Stenosis - diagnostic imaging ; Aortic Valve Stenosis - mortality ; Aortic Valve Stenosis - physiopathology ; Aortic Valve Stenosis - surgery ; Chi-Square Distribution ; chronic kidney disease ; Databases, Factual ; end-stage renal disease ; Female ; Hospital Mortality ; Humans ; in-hospital mortality ; Incidence ; Kidney - physiopathology ; Kidney Failure, Chronic - diagnosis ; Kidney Failure, Chronic - mortality ; Kidney Failure, Chronic - physiopathology ; Kidney Failure, Chronic - therapy ; Linear Models ; Logistic Models ; major adverse cardiovascular event(s) ; Male ; Multivariate Analysis ; Odds Ratio ; Renal Dialysis ; Renal Insufficiency, Chronic - diagnosis ; Renal Insufficiency, Chronic - mortality ; Renal Insufficiency, Chronic - physiopathology ; Renal Insufficiency, Chronic - therapy ; Retrospective Studies ; Risk Factors ; Time Factors ; transcatheter aortic valve replacement ; Transcatheter Aortic Valve Replacement - adverse effects ; Transcatheter Aortic Valve Replacement - mortality ; Treatment Outcome ; United States - epidemiology</subject><ispartof>JACC. Cardiovascular interventions, 2017-10, Vol.10 (20), p.2050-2060</ispartof><rights>2017 American College of Cardiology Foundation</rights><rights>Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-7e21e1e425012c61b8165d9cc0a50144f235b5760ae650edd4ec4d153228d3593</citedby><cites>FETCH-LOGICAL-c356t-7e21e1e425012c61b8165d9cc0a50144f235b5760ae650edd4ec4d153228d3593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1936879817316825$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29050621$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gupta, Tanush</creatorcontrib><creatorcontrib>Goel, Kashish</creatorcontrib><creatorcontrib>Kolte, Dhaval</creatorcontrib><creatorcontrib>Khera, Sahil</creatorcontrib><creatorcontrib>Villablanca, Pedro A.</creatorcontrib><creatorcontrib>Aronow, Wilbert S.</creatorcontrib><creatorcontrib>Bortnick, Anna E.</creatorcontrib><creatorcontrib>Slovut, David P.</creatorcontrib><creatorcontrib>Taub, Cynthia C.</creatorcontrib><creatorcontrib>Kizer, Jorge R.</creatorcontrib><creatorcontrib>Pyo, Robert T.</creatorcontrib><creatorcontrib>Abbott, J. Dawn</creatorcontrib><creatorcontrib>Fonarow, Gregg C.</creatorcontrib><creatorcontrib>Rihal, Charanjit S.</creatorcontrib><creatorcontrib>Garcia, Mario J.</creatorcontrib><creatorcontrib>Bhatt, Deepak L.</creatorcontrib><title>Association of Chronic Kidney Disease With In-Hospital Outcomes of Transcatheter Aortic Valve Replacement</title><title>JACC. Cardiovascular interventions</title><addtitle>JACC Cardiovasc Interv</addtitle><description>This study sought to determine the association of chronic kidney disease (CKD) with in-hospital outcomes of transcatheter aortic valve replacement (TAVR).
CKD is a known independent risk factor for worse outcomes after surgical aortic valve replacement (SAVR). However, data on outcomes of patients with CKD undergoing TAVR are limited, especially in those on chronic dialysis.
The authors used data from the 2012 to 2014 National Inpatient Sample database to identify all patients ≥18 years of age who underwent TAVR. International Classification of Diseases-Ninth Revision-Clinical Modification codes were used to identify patients with no CKD, CKD (without chronic dialysis), or end-stage renal disease (ESRD) on long-term dialysis. Multivariable logistic regression models were constructed using generalized estimating equations to examine in-hospital outcomes.
Of 41,025 patients undergoing TAVR from 2012 to 2014, 25,585 (62.4%) had no CKD, 13,750 (33.5%) had CKD, and 1,690 (4.1%) had ESRD. Compared with patients with no CKD, in-hospital mortality was significantly higher in patients with CKD or ESRD (3.8% vs. 4.5% vs. 8.3%; adjusted odds ratio [no CKD as reference]: 1.39 [95% confidence interval: 1.24 to 1.55] for CKD and 2.58 [95% confidence interval: 2.09 to 3.13] for ESRD). Patients with CKD or ESRD had a higher incidence of major adverse cardiovascular events (composite of death, myocardial infarction, or stroke), net adverse cardiovascular events (composite of major adverse cardiovascular events, major bleeding, or vascular complications), and pacemaker implantation compared with patients without CKD. Acute kidney injury (AKI) and AKI requiring dialysis were associated with several-fold higher risk-adjusted in-hospital mortality in patients in the no CKD and CKD groups. Moreover, the incidence of AKI and AKI requiring dialysis did not decline during the study period.
Patients with CKD or ESRD have worse in-hospital outcomes after TAVR. AKI is associated with higher in-hospital mortality in patients undergoing TAVR and the incidence of AKI has not declined over the years.
[Display omitted]</description><subject>acute kidney injury</subject><subject>Acute Kidney Injury - mortality</subject><subject>Acute Kidney Injury - physiopathology</subject><subject>Acute Kidney Injury - therapy</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aortic Valve - diagnostic imaging</subject><subject>Aortic Valve - physiopathology</subject><subject>Aortic Valve - surgery</subject><subject>Aortic Valve Stenosis - diagnostic imaging</subject><subject>Aortic Valve Stenosis - mortality</subject><subject>Aortic Valve Stenosis - physiopathology</subject><subject>Aortic Valve Stenosis - surgery</subject><subject>Chi-Square Distribution</subject><subject>chronic kidney disease</subject><subject>Databases, Factual</subject><subject>end-stage renal disease</subject><subject>Female</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>in-hospital mortality</subject><subject>Incidence</subject><subject>Kidney - physiopathology</subject><subject>Kidney Failure, Chronic - diagnosis</subject><subject>Kidney Failure, Chronic - mortality</subject><subject>Kidney Failure, Chronic - physiopathology</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Linear Models</subject><subject>Logistic Models</subject><subject>major adverse cardiovascular event(s)</subject><subject>Male</subject><subject>Multivariate Analysis</subject><subject>Odds Ratio</subject><subject>Renal Dialysis</subject><subject>Renal Insufficiency, Chronic - diagnosis</subject><subject>Renal Insufficiency, Chronic - mortality</subject><subject>Renal Insufficiency, Chronic - physiopathology</subject><subject>Renal Insufficiency, Chronic - therapy</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>transcatheter aortic valve replacement</subject><subject>Transcatheter Aortic Valve Replacement - adverse effects</subject><subject>Transcatheter Aortic Valve Replacement - mortality</subject><subject>Treatment Outcome</subject><subject>United States - epidemiology</subject><issn>1936-8798</issn><issn>1876-7605</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1qHDEQhYVx8G8ukEXQ0pueSGpJ3Q3eDJPENjEYguMshaZUw6jplsaSxuDb5Cw5WboZJ8tAQRXFew_eR8gHzhaccf2pX_Tgw0Iw3izYNFIekTPeNrpqNFPH093Vumqbrj0l5zn3jGnWNeKEnIqOKaYFPyP9MucI3hYfA40butqmGDzQb94FfKWffUabkf70ZUvvQnUb884XO9CHfYE4Yp49j8mGDLZssWCiy5iKh9-_nuzwgvQ77gYLOGIol-Tdxg4Z37_tC_Lj65fH1W11_3Bzt1reV1ArXaoGBUeOUijGBWi-brlWrgNgdvpIuRG1WqupoUWtGDonEaTjqhaidbXq6gtydcjdpfi8x1zM6DPgMNiAcZ8N75Rkuq61nKTiIIUUc064MbvkR5teDWdmZmx6MzM2M2PDppGz6eNb_n49ovtn-Qt1ElwfBDi1fPGYTAaPAdD5hFCMi_5_-X8AqV-ODQ</recordid><startdate>20171023</startdate><enddate>20171023</enddate><creator>Gupta, Tanush</creator><creator>Goel, Kashish</creator><creator>Kolte, Dhaval</creator><creator>Khera, Sahil</creator><creator>Villablanca, Pedro A.</creator><creator>Aronow, Wilbert S.</creator><creator>Bortnick, Anna E.</creator><creator>Slovut, David P.</creator><creator>Taub, Cynthia C.</creator><creator>Kizer, Jorge R.</creator><creator>Pyo, Robert T.</creator><creator>Abbott, J. Dawn</creator><creator>Fonarow, Gregg C.</creator><creator>Rihal, Charanjit S.</creator><creator>Garcia, Mario J.</creator><creator>Bhatt, Deepak L.</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20171023</creationdate><title>Association of Chronic Kidney Disease With In-Hospital Outcomes of Transcatheter Aortic Valve Replacement</title><author>Gupta, Tanush ; Goel, Kashish ; Kolte, Dhaval ; Khera, Sahil ; Villablanca, Pedro A. ; Aronow, Wilbert S. ; Bortnick, Anna E. ; Slovut, David P. ; Taub, Cynthia C. ; Kizer, Jorge R. ; Pyo, Robert T. ; Abbott, J. Dawn ; Fonarow, Gregg C. ; Rihal, Charanjit S. ; Garcia, Mario J. ; Bhatt, Deepak L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-7e21e1e425012c61b8165d9cc0a50144f235b5760ae650edd4ec4d153228d3593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>acute kidney injury</topic><topic>Acute Kidney Injury - mortality</topic><topic>Acute Kidney Injury - physiopathology</topic><topic>Acute Kidney Injury - therapy</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aortic Valve - diagnostic imaging</topic><topic>Aortic Valve - physiopathology</topic><topic>Aortic Valve - surgery</topic><topic>Aortic Valve Stenosis - diagnostic imaging</topic><topic>Aortic Valve Stenosis - mortality</topic><topic>Aortic Valve Stenosis - physiopathology</topic><topic>Aortic Valve Stenosis - surgery</topic><topic>Chi-Square Distribution</topic><topic>chronic kidney disease</topic><topic>Databases, Factual</topic><topic>end-stage renal disease</topic><topic>Female</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>in-hospital mortality</topic><topic>Incidence</topic><topic>Kidney - physiopathology</topic><topic>Kidney Failure, Chronic - diagnosis</topic><topic>Kidney Failure, Chronic - mortality</topic><topic>Kidney Failure, Chronic - physiopathology</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Linear Models</topic><topic>Logistic Models</topic><topic>major adverse cardiovascular event(s)</topic><topic>Male</topic><topic>Multivariate Analysis</topic><topic>Odds Ratio</topic><topic>Renal Dialysis</topic><topic>Renal Insufficiency, Chronic - diagnosis</topic><topic>Renal Insufficiency, Chronic - mortality</topic><topic>Renal Insufficiency, Chronic - physiopathology</topic><topic>Renal Insufficiency, Chronic - therapy</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Time Factors</topic><topic>transcatheter aortic valve replacement</topic><topic>Transcatheter Aortic Valve Replacement - adverse effects</topic><topic>Transcatheter Aortic Valve Replacement - mortality</topic><topic>Treatment Outcome</topic><topic>United States - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gupta, Tanush</creatorcontrib><creatorcontrib>Goel, Kashish</creatorcontrib><creatorcontrib>Kolte, Dhaval</creatorcontrib><creatorcontrib>Khera, Sahil</creatorcontrib><creatorcontrib>Villablanca, Pedro A.</creatorcontrib><creatorcontrib>Aronow, Wilbert S.</creatorcontrib><creatorcontrib>Bortnick, Anna E.</creatorcontrib><creatorcontrib>Slovut, David P.</creatorcontrib><creatorcontrib>Taub, Cynthia C.</creatorcontrib><creatorcontrib>Kizer, Jorge R.</creatorcontrib><creatorcontrib>Pyo, Robert T.</creatorcontrib><creatorcontrib>Abbott, J. Dawn</creatorcontrib><creatorcontrib>Fonarow, Gregg C.</creatorcontrib><creatorcontrib>Rihal, Charanjit S.</creatorcontrib><creatorcontrib>Garcia, Mario J.</creatorcontrib><creatorcontrib>Bhatt, Deepak L.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>JACC. Cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gupta, Tanush</au><au>Goel, Kashish</au><au>Kolte, Dhaval</au><au>Khera, Sahil</au><au>Villablanca, Pedro A.</au><au>Aronow, Wilbert S.</au><au>Bortnick, Anna E.</au><au>Slovut, David P.</au><au>Taub, Cynthia C.</au><au>Kizer, Jorge R.</au><au>Pyo, Robert T.</au><au>Abbott, J. Dawn</au><au>Fonarow, Gregg C.</au><au>Rihal, Charanjit S.</au><au>Garcia, Mario J.</au><au>Bhatt, Deepak L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Chronic Kidney Disease With In-Hospital Outcomes of Transcatheter Aortic Valve Replacement</atitle><jtitle>JACC. Cardiovascular interventions</jtitle><addtitle>JACC Cardiovasc Interv</addtitle><date>2017-10-23</date><risdate>2017</risdate><volume>10</volume><issue>20</issue><spage>2050</spage><epage>2060</epage><pages>2050-2060</pages><issn>1936-8798</issn><eissn>1876-7605</eissn><abstract>This study sought to determine the association of chronic kidney disease (CKD) with in-hospital outcomes of transcatheter aortic valve replacement (TAVR).
CKD is a known independent risk factor for worse outcomes after surgical aortic valve replacement (SAVR). However, data on outcomes of patients with CKD undergoing TAVR are limited, especially in those on chronic dialysis.
The authors used data from the 2012 to 2014 National Inpatient Sample database to identify all patients ≥18 years of age who underwent TAVR. International Classification of Diseases-Ninth Revision-Clinical Modification codes were used to identify patients with no CKD, CKD (without chronic dialysis), or end-stage renal disease (ESRD) on long-term dialysis. Multivariable logistic regression models were constructed using generalized estimating equations to examine in-hospital outcomes.
Of 41,025 patients undergoing TAVR from 2012 to 2014, 25,585 (62.4%) had no CKD, 13,750 (33.5%) had CKD, and 1,690 (4.1%) had ESRD. Compared with patients with no CKD, in-hospital mortality was significantly higher in patients with CKD or ESRD (3.8% vs. 4.5% vs. 8.3%; adjusted odds ratio [no CKD as reference]: 1.39 [95% confidence interval: 1.24 to 1.55] for CKD and 2.58 [95% confidence interval: 2.09 to 3.13] for ESRD). Patients with CKD or ESRD had a higher incidence of major adverse cardiovascular events (composite of death, myocardial infarction, or stroke), net adverse cardiovascular events (composite of major adverse cardiovascular events, major bleeding, or vascular complications), and pacemaker implantation compared with patients without CKD. Acute kidney injury (AKI) and AKI requiring dialysis were associated with several-fold higher risk-adjusted in-hospital mortality in patients in the no CKD and CKD groups. Moreover, the incidence of AKI and AKI requiring dialysis did not decline during the study period.
Patients with CKD or ESRD have worse in-hospital outcomes after TAVR. AKI is associated with higher in-hospital mortality in patients undergoing TAVR and the incidence of AKI has not declined over the years.
[Display omitted]</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>29050621</pmid><doi>10.1016/j.jcin.2017.07.044</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | acute kidney injury Acute Kidney Injury - mortality Acute Kidney Injury - physiopathology Acute Kidney Injury - therapy Aged Aged, 80 and over Aortic Valve - diagnostic imaging Aortic Valve - physiopathology Aortic Valve - surgery Aortic Valve Stenosis - diagnostic imaging Aortic Valve Stenosis - mortality Aortic Valve Stenosis - physiopathology Aortic Valve Stenosis - surgery Chi-Square Distribution chronic kidney disease Databases, Factual end-stage renal disease Female Hospital Mortality Humans in-hospital mortality Incidence Kidney - physiopathology Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - mortality Kidney Failure, Chronic - physiopathology Kidney Failure, Chronic - therapy Linear Models Logistic Models major adverse cardiovascular event(s) Male Multivariate Analysis Odds Ratio Renal Dialysis Renal Insufficiency, Chronic - diagnosis Renal Insufficiency, Chronic - mortality Renal Insufficiency, Chronic - physiopathology Renal Insufficiency, Chronic - therapy Retrospective Studies Risk Factors Time Factors transcatheter aortic valve replacement Transcatheter Aortic Valve Replacement - adverse effects Transcatheter Aortic Valve Replacement - mortality Treatment Outcome United States - epidemiology |
| title | Association of Chronic Kidney Disease With In-Hospital Outcomes of Transcatheter Aortic Valve Replacement |
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