Endocannabinoids modulate stress-induced suppression of hippocampal cell proliferation and activation of defensive behaviours

The endocannabinoid system has been shown to regulate both the hypothalamic–pituitary–adrenal (HPA) axis and emotionality. The present experiment was designed to examine whether pharmacological modulation of the endocannabinoid system would affect the suppression of hippocampal cell proliferation an...

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Veröffentlicht in:	The European journal of neuroscience 2006-10, Vol.24 (7), p.1845-1849
Hauptverfasser:	Hill, Matthew N., Kambo, Jaspreet S., Sun, Jane C., Gorzalka, Boris B., Galea, Liisa A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggression - drug effects Aggression - physiology Animals anxiety Arachidonic Acids - pharmacology Behavior, Animal Bromodeoxyuridine - metabolism Cannabinoid Receptor Modulators - antagonists & inhibitors Cannabinoid Receptor Modulators - metabolism Cannabinoid Receptor Modulators - pharmacology CB1 receptor Cell Count - methods Cell Proliferation - drug effects defensive burying dentate gyrus Endocannabinoids Enzyme Inhibitors - pharmacology Hippocampus - cytology Immunohistochemistry - methods Male Neural Inhibition - drug effects Neural Inhibition - physiology neurogenesis Odorants Piperidines - pharmacology Pyrazoles - pharmacology Rats Rats, Sprague-Dawley Stress, Psychological - physiopathology Thiazoles - administration & dosage TMT
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