ORIGINAL ARTICLE: A beta induces endoplasmic reticulum stress causing possible proteasome impairment via the endoplasmic reticulum-associated degradation pathway

Background:Accumulation of beta -amyloid is a major pathology of Alzheimer's disease (AD). As in other neurodegenerative diseases, it is also reported that proteasome activity is deteriorated in post-mortem brains of AD patients. However, the mechanism of proteasomal dysfunction in AD remains u...

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Veröffentlicht in:	Psychogeriatrics 2006-09, Vol.6 (3), p.100-106
Hauptverfasser:	Kanayama, Daisuke, Kudo, Takashi, Kimura, Ryo, Tabuchi, Nobuhiko, Fukumori, Akio, Morihara, Takeshi, Tagami, Shinji, Tanii, Hisashi, Okochi, Masayasu, Kamino, Kojin, Tanaka, Toshihisa, Imaizumi, Kazunori, Tabira, Takeshi, Takeda, Masatoshi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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