ANTIMICROBIAL PEPTIDE DEFENSES IN THE SALAMANDER, AMBYSTOMA TIGRINUM, AGAINST EMERGING AMPHIBIAN PATHOGENS

Skin peptides were collected from living Ambystoma tigrinum larvae and adults and tested against two emerging pathogens, Batrachochytrium dendrobatidis and the Ambystoma tigrinum virus (ATV), as well as bacteria isolated from A. tigrinum. Natural mixtures of skin peptides were found to inhibit growt...

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Veröffentlicht in:Journal of wildlife diseases 2008-04, Vol.44 (2), p.226-236
Hauptverfasser: Shea, Brandon, Davidson, Elizabeth W, Parr, Luke, Rollins-Smith, Louise
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container_title Journal of wildlife diseases
container_volume 44
creator Shea, Brandon
Davidson, Elizabeth W
Parr, Luke
Rollins-Smith, Louise
description Skin peptides were collected from living Ambystoma tigrinum larvae and adults and tested against two emerging pathogens, Batrachochytrium dendrobatidis and the Ambystoma tigrinum virus (ATV), as well as bacteria isolated from A. tigrinum. Natural mixtures of skin peptides were found to inhibit growth of B. dendrobatidis, Staphylococcus aureus, and Klebsiella sp., but activity against ATV was unpredictable. Skin peptides collected from salamanders held at three environmentally relevant temperatures differed in activity against B. dendrobatidis. Activity of the A. tigrinum skin peptides was found to be strongly influenced by pH.
doi_str_mv 10.1043/0090-3558(2008)44[226:APDITS]2.0.CO;2
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source BioOne Open Access Titles; Allen Press Journals; EZB-FREE-00999 freely available EZB journals
subjects Ambystoma tigrinum
Batrachochytrium dendrobatidis
Caudata
Klebsiella
Staphylococcus aureus
title ANTIMICROBIAL PEPTIDE DEFENSES IN THE SALAMANDER, AMBYSTOMA TIGRINUM, AGAINST EMERGING AMPHIBIAN PATHOGENS
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