Systemic Inflammation Induced by microRNAs: Endometriosis-Derived Alterations in Circulating microRNA 125b-5p and Let-7b-5p Regulate Macrophage Cytokine Production

Endometriosis is characterized by aberrant inflammation. We previously reported increased levels of microRNA (miRNA) 125b-5p and decreased levels of miRNA Let-7b-5p in serum of patients with endometriosis. Determine the regulatory function of miRNAs 125b-5p and Let-7b-5p on production of proinflamma...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2018-01, Vol.103 (1), p.64-74
Hauptverfasser:	Nematian, Sepide E, Mamillapalli, Ramanaiah, Kadakia, Trisha S, Majidi Zolbin, Masoumeh, Moustafa, Sarah, Taylor, Hugh S
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell differentiation Cytokines Endometriosis Enzyme-linked immunosorbent assay IL-1β Inflammation Interleukin 6 Interleukin 8 Intracellular Macrophages MicroRNAs miRNA mRNA Polymerase chain reaction Transfection Tumor necrosis factor-TNF Tumor necrosis factor-α
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