In utero exposure to nicotine and chlorpyrifos alone, and in combination produces persistent sensorimotor deficits and Purkinje neuron loss in the cerebellum of adult offspring rats

This study was carried out to investigate the effect of in utero exposure to the cholinotoxicants, nicotine and chlorpyrifos, alone or in combination on neurobehavioral alterations and neuronal morphology latter in adult age. In the present study, 90 days old (corresponding to a human adult age) mal...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of toxicology 2006-09, Vol.80 (9), p.620-631
Hauptverfasser:	ABOU-DONIA, Mohamed B, KHAN, Wasiuddin A, DECHKOVSKAIA, Anjelika M, GOLDSTEIN, Larry B, BULLMAN, Sarah L, ABDEL-RAHMAN, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Animals Behavior, Animal - drug effects Biological and medical sciences Cell Death - drug effects Chlorpyrifos - toxicity Cholinesterase Inhibitors - toxicity Cholinesterases - blood Drug Therapy, Combination Female Genetics Infusion Pumps, Implantable Injections, Subcutaneous Male Maternal Exposure - adverse effects Medical sciences Nicotine - toxicity Pesticides, fertilizers and other agrochemicals toxicology Pregnancy Prenatal Exposure Delayed Effects Psychomotor Performance - drug effects Purkinje Cells - drug effects Purkinje Cells - pathology Rats Rodents Tobacco, tobacco smoking Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!