Enhancing Photochemical Internalization of DOX through a Porphyrin-based Amphiphilic Block Copolymer

Drug resistance is a primary obstacle that seriously reduces the therapy efficiency of most chemotherapeutic agents. To address this issue, the photochemical internalization (PCI) was employed to help the anticancer drug escape from lysosome and improve their translocation to the nucleus. A pH-sensi...

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Veröffentlicht in:Biomacromolecules 2017-12, Vol.18 (12), p.3992-4001
Hauptverfasser: Tian, Jia, Xu, Lei, Xue, Yudong, Jiang, Xiaoze, Zhang, Weian
Format: Artikel
Sprache:eng
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