The Evolution of Genetic Architecture
Genetic architecture, the structure of the mapping from genotype to phenotype, determines the variational properties of the phenotype and is instrumental in understanding its evolutionary potential. Throughout most of the history of evolutionary biology, genetic architecture has been treated as a gi...
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Veröffentlicht in: | Annual review of ecology, evolution, and systematics evolution, and systematics, 2006-01, Vol.37 (1), p.123-157 |
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container_title | Annual review of ecology, evolution, and systematics |
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description | Genetic architecture, the structure of the mapping from genotype to phenotype, determines the variational properties of the phenotype and is instrumental in understanding its evolutionary potential. Throughout most of the history of evolutionary biology, genetic architecture has been treated as a given set of parameters and not as a set of dynamic variables. The past decade has seen renewed interest in incorporating the genotype-phenotype map as a dynamical part of population genetics. This has been aided by several conceptual advances. I review these developments with emphasis on recent theoretical work on the evolution of genetic architecture and evolvability. |
doi_str_mv | 10.1146/annurev.ecolsys.37.091305.110224 |
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Psychology</subject><subject>General aspects</subject><subject>Genetic mutation</subject><subject>Genetic variation</subject><subject>Genetics</subject><subject>Genomics</subject><subject>Genotype & phenotype</subject><subject>Genotypes</subject><subject>Phenotypic traits</subject><subject>Population genetics</subject><subject>Quantitative genetics</subject><subject>Theory</subject><issn>1543-592X</issn><issn>1545-2069</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNpdkF1LwzAUhoMoOKc_QSjCxJvWfDbJnWPMKQy8meBdyNKUdXTNTNrB_v0yWxS8OgfOw_seHgCeEMwQovmzbprO20NmjavDMWSEZ1AiAlk8Q4zpBRghRlmKYS4vf3aSMom_rsFNCFt4RgQagclqY5P5wdVdW7kmcWWysI1tK5NMvdlUrTVtrLkFV6Wug70b5hh8vs5Xs7d0-bF4n02XqWactSllQiKDKS8hkQWnJdFUWrYuLOQUE62FwUhjxIsCFXRdEpjrnDK8FgQKDTEZg8c-d-_dd2dDq3ZVMLaudWNdFxSSDAnO8wg-_AO3rvNN_E3hCFGKJI_QSw8Z70LwtlR7X-20PyoE1VmiGiSqQaIiXPUSVS8xRkyGHh2MrkuvG1OFvxxBcipyFrn7ntuG1vnfO4GQEIElOQG7NH9t</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>Hansen, Thomas F.</creator><general>Annual Reviews</general><general>Annual Reviews, Inc</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>20060101</creationdate><title>The Evolution of Genetic Architecture</title><author>Hansen, Thomas F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a575t-45891c247f039d74f3a49e5bde07423aa8c21a217dd1d4bf306a6452b8308a023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Animal and plant ecology</topic><topic>Animal, plant and microbial ecology</topic><topic>Architecture</topic><topic>Biological and medical sciences</topic><topic>Epistasis</topic><topic>Evolution</topic><topic>Evolutionary biology</topic><topic>Evolutionary genetics</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Genetic mutation</topic><topic>Genetic variation</topic><topic>Genetics</topic><topic>Genomics</topic><topic>Genotype & phenotype</topic><topic>Genotypes</topic><topic>Phenotypic traits</topic><topic>Population genetics</topic><topic>Quantitative genetics</topic><topic>Theory</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hansen, Thomas F.</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Annual review of ecology, evolution, and systematics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hansen, Thomas F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Evolution of Genetic Architecture</atitle><jtitle>Annual review of ecology, evolution, and systematics</jtitle><date>2006-01-01</date><risdate>2006</risdate><volume>37</volume><issue>1</issue><spage>123</spage><epage>157</epage><pages>123-157</pages><issn>1543-592X</issn><eissn>1545-2069</eissn><abstract>Genetic architecture, the structure of the mapping from genotype to phenotype, determines the variational properties of the phenotype and is instrumental in understanding its evolutionary potential. 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source | Jstor Complete Legacy; Annual Reviews Complete A-Z List |
subjects | Animal and plant ecology Animal, plant and microbial ecology Architecture Biological and medical sciences Epistasis Evolution Evolutionary biology Evolutionary genetics Fundamental and applied biological sciences. Psychology General aspects Genetic mutation Genetic variation Genetics Genomics Genotype & phenotype Genotypes Phenotypic traits Population genetics Quantitative genetics Theory |
title | The Evolution of Genetic Architecture |
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