PTGER2 activation induces PTGS-2 and growth factor gene expression in endometrial epithelial cells of cattle

The prostaglandin E2 receptor 2 (PTGER2) is present in the endometrium and its gene expression is accompanied with endometrial growth, however, it is unknown whether there is endometrial repair through stimulation of growth factor gene expression that is promoted by PTGER2 activation in cattle. The...

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Veröffentlicht in:	Animal reproduction science 2017-12, Vol.187, p.54-63
Hauptverfasser:	Gao, Long, Liu, Bo, Mao, Wei, Gao, Ruifeng, Zhang, Shuangyi, Duritahala, Fu, Changqi, Shen, Yuan, Zhang, Ying, Zhang, Nan, Wu, Jindi, Deng, Yang, Wu, Xing, Cao, Jinshan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alprostadil - analogs & derivatives Alprostadil - pharmacology Animals Bovine endometrial epithelial cell Cattle - genetics Cattle - metabolism Cells, Cultured Cyclooxygenase 2 - genetics Cyclooxygenase 2 - metabolism Dinoprostone - genetics Dinoprostone - metabolism Endometrium - cytology Endometrium - drug effects Endometrium - metabolism Epithelial Cells - cytology Epithelial Cells - drug effects Epithelial Cells - metabolism Female Gene Expression Regulation - drug effects Growth factors Intercellular Signaling Peptides and Proteins - genetics Interleukin-8 - genetics Interleukin-8 - metabolism MAP Kinase Signaling System - drug effects Prostaglandin Antagonists - pharmacology PTGER2 activation PTGS-2 Receptors, Prostaglandin E, EP2 Subtype - chemistry Receptors, Prostaglandin E, EP2 Subtype - genetics Receptors, Prostaglandin E, EP2 Subtype - metabolism Transforming Growth Factor beta1 - genetics Transforming Growth Factor beta1 - metabolism Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Xanthones - pharmacology
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