Synthesis of Secondary Aromatic Amides via Pd-Catalyzed Aminocarbonylation of Aryl Halides Using Carbamoylsilane as an Amide Source

Using N-methoxymethyl-N-organylcarbamoyl­(trimethyl)­silanes as secondary amides source, the direct transformation of aryl halides into the corresponding secondary aromatic amides via palladium-catalyzed aminocarbonylation is described. The reactions tolerated a broad range of functional groups on t...

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Veröffentlicht in:Journal of organic chemistry 2017-11, Vol.82 (21), p.11603-11608
Hauptverfasser: Tong, Wenting, Cao, Pei, Liu, Yanhong, Chen, Jianxin
Format: Artikel
Sprache:eng
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