The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

Key Points The DNA methyltransferases (DNMTs) are a conserved family of cytosine methylases with a key role in epigenetic regulation. DNMT activity is highly regulated. Key regulatory mechanisms include molecular interactions, post-translational modifications, alternative splicing and gene duplicati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature reviews. Genetics 2018-02, Vol.19 (2), p.81-92
1. Verfasser:	Lyko, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	631/181/2474 631/337/176/1988 631/337/572 631/337/574/1793 Agriculture Animal Genetics and Genomics Biomedicine Cancer Research Deoxyribonucleic acid DNA DNA methylation DNA methyltransferase DNMT1 protein Enzymes Epigenetic inheritance Epigenetics Gene Function Gene regulation Gene silencing Genetic research Human Genetics Methyltransferases Post-transcription Properties review-article Transcription activation tRNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!