Neither linoleic acid nor arachidonic acid promote white adipose tissue inflammation in Fads2-/- mice fed low fat diets

Dietary n-6 polyunsaturated fatty acids (PUFA) are widely perceived to promote inflammation and contribute to the development of chronic diseases. This dogma has been recently questioned due to evidence that n-6 PUFA, specifically linoleic acid (LA, 18:2n-6) and arachidonic acid (AA, 20:4n-6), do no...

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Veröffentlicht in:	Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 2017-11, Vol.126, p.84-91
Hauptverfasser:	Suitor, Katherine, Payne, George W., Sarr, Ousseynou, Abdelmagid, Salma, Nakamura, Manabu T., Ma, David WL, Mutch, David M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - drug effects Adipose Tissue, White - drug effects Adipose Tissue, White - metabolism Animals Arachidonic acid Arachidonic Acid - administration & dosage Arachidonic Acid - adverse effects Delta-6 desaturase Diet, Fat-Restricted - adverse effects Dietary Fats - metabolism Epididymal fat Fatty Acid Desaturases - genetics Fatty Acid Desaturases - metabolism Fatty Acids, Unsaturated - metabolism Gene Expression Regulation - drug effects Inflammation Inflammation - chemically induced Inflammation - genetics Inflammation - metabolism Inflammation - pathology Inguinal fat Linoleic acid Linoleic Acid - administration & dosage Linoleic Acid - adverse effects Lipid Metabolism - genetics Mice Phospholipids - metabolism Signal Transduction - drug effects Triglycerides - metabolism
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