Lead, Genetic Susceptibility, and Risk of Adult Brain Tumors

Background: Although few etiologic factors for brain tumors have been identified, limited data suggest that lead may increase the risk of brain tumors, particularly meningioma. The ALAD G177C polymorphism affects the toxicokinetics of lead and may confer genetic susceptibility to adverse effects of...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2006-12, Vol.15 (12), p.2514-2520
Hauptverfasser:	RAJARAMAN, Preetha, STEWART, Patricia A, LOEFFLER, Jay, SHAPIRO, William R, SELKER, Robert G, INSKIP, Peter D, SAMET, Jonathan M, SCHWARTZ, Brian S, LINET, Martha S, SHELIA HOAR ZAHM, ROTHMAN, Nathaniel, YEAGER, Meredith, FINE, Howard A, BLACK, Peter M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over ALAD Arizona Biological and medical sciences brain Brain Neoplasms - chemically induced Brain Neoplasms - epidemiology Brain Neoplasms - genetics case-control Case-Control Studies Female Genetic Predisposition to Disease Genotype glioma Glioma - chemically induced Glioma - epidemiology Glioma - genetics Humans lead Lead - adverse effects Lead - blood Male Massachusetts - epidemiology Medical sciences meningioma Meningioma - chemically induced Meningioma - epidemiology Meningioma - genetics Middle Aged neoplasm Neurology Occupational Exposure - adverse effects Pennsylvania - epidemiology polymorphism tumor Tumors Tumors of the nervous system. Phacomatoses
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