Trophic effect in MCF-7 cells of ER alpha 17p, a peptide corresponding to a platform regulatory motif of the estrogen receptor alpha - Underlying mechanisms

As yet, estrogen receptor alpha (ER alpha ) inhibitors used in clinical practice target a unique site, i.e. the hormone-binding pocket. With the aim of discovering other potential therapeutic targets in the receptor, we studied its AF-2a domain, a site that proves to be critical for ligand-independe...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 2008-03, Vol.109 (1-2), p.138-149
Hauptverfasser:	Gallo, Dominique, Haddad, Iman, Duvillier, Hugues, Jacquemotte, Francoise, Laieos, Ioanna, Laurent, Guy, Jacquot, Yves, Vinh, Joelle, Leclercq, Guy
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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