Thermo-responsive self-immolative nanoassemblies: direct and indirect triggering
A thermo-responsive end-cap based on a retro-Diels-Alder and subsequent furan elimination reaction was developed. It was used to cap poly(ethyl glyoxylate), allowing end-to-end depolymerization upon thermal triggering. Using block copolymers, thermo-responsive micelles and vesicles were prepared and...
Gespeichert in:
| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2017-11, Vol.53 (89), p.1268-1271 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1271 |
|---|---|
| container_issue | 89 |
| container_start_page | 1268 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | 53 |
| creator | Fan, Bo Trant, John F Hemery, Gauvin Sandre, Olivier Gillies, Elizabeth R |
| description | A thermo-responsive end-cap based on a retro-Diels-Alder and subsequent furan elimination reaction was developed. It was used to cap poly(ethyl glyoxylate), allowing end-to-end depolymerization upon thermal triggering. Using block copolymers, thermo-responsive micelles and vesicles were prepared and shown to disassemble upon heating. Thermal degradation could also be triggered indirectly by magnetic field hyperthermia after incorporation of iron oxide nanoparticles into the assemblies.
A new thermo-responsive end-cap was developed and applied to self-immolative vesicles and micelles with both direct and indirect thermal triggering. |
| doi_str_mv | 10.1039/c7cc06410a |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1950417780</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1950417780</sourcerecordid><originalsourceid>FETCH-LOGICAL-c379t-251a1ee87b02c62558f3531e0410f176618e28694e178568544d2dc182edc49b3</originalsourceid><addsrcrecordid>eNpFkctLAzEQxoMoVqsX70qPKqxmspuXt7KoFQp6qOBtSbOzbWQfNdkW_O_dtbXmMq8f3zBfCLkAegc01vdWWktFAtQckBOIRRLxRH0c9jnXkYwTPiCnIXzS7gFXx2TANGVMC3FC3mZL9FUTeQyrpg5ug6OAZRG5qmpK0_Z1berGhIDVvHQYHka582jbkanzkat3RevdYoHe1YszclSYMuD5Lg7J-9PjLJ1E09fnl3Q8jWwsdRsxDgYQlZxTZgXjXBUxjwFpd0YBUghQyJTQCYJUXCieJDnLLSiGuU30PB6Sm63u0pTZyrvK-O-sMS6bjKdZ36MggAktN9Cx11t25ZuvNYY2q1ywWJamxmYdMtC82yuloh16u0Wtb0LwWOy1gWa921kq0_TX7XEHX-101_MK8z36Z28HXG4BH-x--v9d8Q_XJoKh</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1950417780</pqid></control><display><type>article</type><title>Thermo-responsive self-immolative nanoassemblies: direct and indirect triggering</title><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Fan, Bo ; Trant, John F ; Hemery, Gauvin ; Sandre, Olivier ; Gillies, Elizabeth R</creator><creatorcontrib>Fan, Bo ; Trant, John F ; Hemery, Gauvin ; Sandre, Olivier ; Gillies, Elizabeth R</creatorcontrib><description>A thermo-responsive end-cap based on a retro-Diels-Alder and subsequent furan elimination reaction was developed. It was used to cap poly(ethyl glyoxylate), allowing end-to-end depolymerization upon thermal triggering. Using block copolymers, thermo-responsive micelles and vesicles were prepared and shown to disassemble upon heating. Thermal degradation could also be triggered indirectly by magnetic field hyperthermia after incorporation of iron oxide nanoparticles into the assemblies.
A new thermo-responsive end-cap was developed and applied to self-immolative vesicles and micelles with both direct and indirect thermal triggering.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c7cc06410a</identifier><identifier>PMID: 29022966</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Chemical Sciences ; Condensed Matter ; Material chemistry ; Physics ; Polymers ; Soft Condensed Matter</subject><ispartof>Chemical communications (Cambridge, England), 2017-11, Vol.53 (89), p.1268-1271</ispartof><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c379t-251a1ee87b02c62558f3531e0410f176618e28694e178568544d2dc182edc49b3</citedby><cites>FETCH-LOGICAL-c379t-251a1ee87b02c62558f3531e0410f176618e28694e178568544d2dc182edc49b3</cites><orcidid>0000-0002-4780-4968 ; 0000-0002-1815-2702 ; 0000-0002-3983-2248</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29022966$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-01612697$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Fan, Bo</creatorcontrib><creatorcontrib>Trant, John F</creatorcontrib><creatorcontrib>Hemery, Gauvin</creatorcontrib><creatorcontrib>Sandre, Olivier</creatorcontrib><creatorcontrib>Gillies, Elizabeth R</creatorcontrib><title>Thermo-responsive self-immolative nanoassemblies: direct and indirect triggering</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>A thermo-responsive end-cap based on a retro-Diels-Alder and subsequent furan elimination reaction was developed. It was used to cap poly(ethyl glyoxylate), allowing end-to-end depolymerization upon thermal triggering. Using block copolymers, thermo-responsive micelles and vesicles were prepared and shown to disassemble upon heating. Thermal degradation could also be triggered indirectly by magnetic field hyperthermia after incorporation of iron oxide nanoparticles into the assemblies.
A new thermo-responsive end-cap was developed and applied to self-immolative vesicles and micelles with both direct and indirect thermal triggering.</description><subject>Chemical Sciences</subject><subject>Condensed Matter</subject><subject>Material chemistry</subject><subject>Physics</subject><subject>Polymers</subject><subject>Soft Condensed Matter</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpFkctLAzEQxoMoVqsX70qPKqxmspuXt7KoFQp6qOBtSbOzbWQfNdkW_O_dtbXmMq8f3zBfCLkAegc01vdWWktFAtQckBOIRRLxRH0c9jnXkYwTPiCnIXzS7gFXx2TANGVMC3FC3mZL9FUTeQyrpg5ug6OAZRG5qmpK0_Z1berGhIDVvHQYHka582jbkanzkat3RevdYoHe1YszclSYMuD5Lg7J-9PjLJ1E09fnl3Q8jWwsdRsxDgYQlZxTZgXjXBUxjwFpd0YBUghQyJTQCYJUXCieJDnLLSiGuU30PB6Sm63u0pTZyrvK-O-sMS6bjKdZ36MggAktN9Cx11t25ZuvNYY2q1ywWJamxmYdMtC82yuloh16u0Wtb0LwWOy1gWa921kq0_TX7XEHX-101_MK8z36Z28HXG4BH-x--v9d8Q_XJoKh</recordid><startdate>20171107</startdate><enddate>20171107</enddate><creator>Fan, Bo</creator><creator>Trant, John F</creator><creator>Hemery, Gauvin</creator><creator>Sandre, Olivier</creator><creator>Gillies, Elizabeth R</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><orcidid>https://orcid.org/0000-0002-4780-4968</orcidid><orcidid>https://orcid.org/0000-0002-1815-2702</orcidid><orcidid>https://orcid.org/0000-0002-3983-2248</orcidid></search><sort><creationdate>20171107</creationdate><title>Thermo-responsive self-immolative nanoassemblies: direct and indirect triggering</title><author>Fan, Bo ; Trant, John F ; Hemery, Gauvin ; Sandre, Olivier ; Gillies, Elizabeth R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c379t-251a1ee87b02c62558f3531e0410f176618e28694e178568544d2dc182edc49b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Chemical Sciences</topic><topic>Condensed Matter</topic><topic>Material chemistry</topic><topic>Physics</topic><topic>Polymers</topic><topic>Soft Condensed Matter</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fan, Bo</creatorcontrib><creatorcontrib>Trant, John F</creatorcontrib><creatorcontrib>Hemery, Gauvin</creatorcontrib><creatorcontrib>Sandre, Olivier</creatorcontrib><creatorcontrib>Gillies, Elizabeth R</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fan, Bo</au><au>Trant, John F</au><au>Hemery, Gauvin</au><au>Sandre, Olivier</au><au>Gillies, Elizabeth R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thermo-responsive self-immolative nanoassemblies: direct and indirect triggering</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2017-11-07</date><risdate>2017</risdate><volume>53</volume><issue>89</issue><spage>1268</spage><epage>1271</epage><pages>1268-1271</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>A thermo-responsive end-cap based on a retro-Diels-Alder and subsequent furan elimination reaction was developed. It was used to cap poly(ethyl glyoxylate), allowing end-to-end depolymerization upon thermal triggering. Using block copolymers, thermo-responsive micelles and vesicles were prepared and shown to disassemble upon heating. Thermal degradation could also be triggered indirectly by magnetic field hyperthermia after incorporation of iron oxide nanoparticles into the assemblies.
A new thermo-responsive end-cap was developed and applied to self-immolative vesicles and micelles with both direct and indirect thermal triggering.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>29022966</pmid><doi>10.1039/c7cc06410a</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-4780-4968</orcidid><orcidid>https://orcid.org/0000-0002-1815-2702</orcidid><orcidid>https://orcid.org/0000-0002-3983-2248</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2017-11, Vol.53 (89), p.1268-1271 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1950417780 |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Chemical Sciences Condensed Matter Material chemistry Physics Polymers Soft Condensed Matter |
| title | Thermo-responsive self-immolative nanoassemblies: direct and indirect triggering |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T22%3A43%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Thermo-responsive%20self-immolative%20nanoassemblies:%20direct%20and%20indirect%20triggering&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Fan,%20Bo&rft.date=2017-11-07&rft.volume=53&rft.issue=89&rft.spage=1268&rft.epage=1271&rft.pages=1268-1271&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/c7cc06410a&rft_dat=%3Cproquest_pubme%3E1950417780%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1950417780&rft_id=info:pmid/29022966&rfr_iscdi=true |