Carbonic anhydrase inhibitors: Synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamide s

A series of 2-(hydrazinocarbonyl)-3-substitutedphenyl-1H-indole-5-sulfonamides possessing various 2- , 3- or 4- substituted phenyl groups with methyl-, halogeno- and methoxy- functionalities, as well as the perfluorophenyl moiety have been synthesized and evaluated as inhibitors of 13 catalytically...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2008-10, Vol.16 (20), p.9113-9120
Hauptverfasser: Guezel, Oezlen, Innocenti, Alessio, Scozzafava, Andrea, Salman, Aydin, Parkkila, Seppo, Hilvo, Mika, Supuran, Claudiu T
Format: Artikel
Sprache:eng
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