Cell Cycle Protein Expression in Neuroendocrine Tumors: Association of CDK4/CDK6, CCND1, and Phosphorylated Retinoblastoma Protein With Proliferative Index

Dysregulation of the cell cycle has been observed and implicated as an etiologic factor in a range of human malignancies, but remains relatively unstudied in neuroendocrine tumors (NETs). We evaluated expression of key proteins involved in cell cycle regulation in a large cohort of NETs. We evaluate...

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Veröffentlicht in:Pancreas 2017-11, Vol.46 (10), p.1347-1353
Hauptverfasser: Shi, Yan, Qian, Zhi Rong, Zhang, Sui, Li, Wanwan, Masugi, Yohei, Li, Tingting, Chan, Jennifer A, Yang, Juhong, Da Silva, Annacarolina, Gu, Mancang, Liu, Li, Hamada, Tsuyoshi, Kosumi, Keisuke, Dutton, Trevor, Brais, Lauren K, Nishihara, Reiko, Fuchs, Charles S, Ogino, Shuji, Kulke, Matthew H
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Sprache:eng
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