Effects of maternal separation and antidepressant drug on epigenetic regulation of the brain‐derived neurotrophic factor exon I promoter in the adult rat hippocampus

Aim Early life stress can induce epigenetic changes through genetic and environmental interactions and is a risk factor for depression. Brain‐derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of depression and antidepressant drug action. We investigated epigenetic changes...

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