Efficacy of long pulse Nd:YAG laser versus fractional Er:YAG laser in the treatment of hand wrinkles
There are different modalities for hand rejuvenation. Fractional Er:YAG laser and long pulse Nd:YAG laser were introduced for treating hand wrinkles. We plan to compare fractional Er:YAG laser and long pulse Nd:YAG laser in a randomized controlled double-blind design with multiple sessions and large...
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| Veröffentlicht in: | Lasers in medical science 2018-04, Vol.33 (3), p.461-467 |
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| creator | Robati, Reza M. Asadi, Elmira Shafiee, Anoosh Namazi, Nastaran Talebi, Atefeh |
| description | There are different modalities for hand rejuvenation. Fractional Er:YAG laser and long pulse Nd:YAG laser were introduced for treating hand wrinkles. We plan to compare fractional Er:YAG laser and long pulse Nd:YAG laser in a randomized controlled double-blind design with multiple sessions and larger sample size in comparison with previous studies. Thirty-three participants with hand wrinkles entered this study. They were randomly allocated to undergo three monthly laser treatments on each hand, one with a fractional Er:YAG laser and the other with a long pulse Nd:YAG laser. The evaluations included assessment of clinical improvement determined by two independent dermatologists not enrolled in the treatment along with measuring skin biomechanical property of hands using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT). Moreover, potential side effects and patients’ satisfaction have been documented at baseline, 1 month after each treatment, and 3 months after the final treatment session. Clinical evaluation revealed both modalities significantly reduce hand wrinkles (
p
value |
| doi_str_mv | 10.1007/s10103-017-2351-2 |
| format | Article |
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p
value < 0.05), with no significant difference between two lasers. Mean CRRT values also decreased significantly after the laser treatment compared to those of the baseline in both laser groups. There was no serious persistent side effect after both laser treatments. Both fractional Er:YAG and long pulse Nd:YAG lasers show substantial clinical improvement of hand skin wrinkles with no serious side effects. However, combination treatment by these lasers along with the other modalities such as fat transfer could lead to better outcomes in hand rejuvenation. Trial registration: IRCT2016032020468N4</description><identifier>ISSN: 0268-8921</identifier><identifier>EISSN: 1435-604X</identifier><identifier>DOI: 10.1007/s10103-017-2351-2</identifier><identifier>PMID: 28990118</identifier><language>eng</language><publisher>London: Springer London</publisher><subject>Adult ; Aged ; Biomechanical Phenomena ; Biomechanics ; Clinical trials ; Dentistry ; Double-Blind Method ; Female ; Follow-Up Studies ; Hand ; Hand - radiation effects ; Humans ; Lasers ; Lasers, Solid-State - adverse effects ; Lasers, Solid-State - therapeutic use ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neodymium lasers ; Optical Devices ; Optics ; Original Article ; Patient Satisfaction ; Photonics ; Quantum Optics ; Semiconductor lasers ; Side effects ; Skin ; Skin Aging - radiation effects ; Time Factors ; Treatment Outcome ; YAG lasers</subject><ispartof>Lasers in medical science, 2018-04, Vol.33 (3), p.461-467</ispartof><rights>Springer-Verlag London Ltd. 2017</rights><rights>Lasers in Medical Science is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-4e21212e4e2148efb226109fce83f85b70d019864cd4c56ab408a3a9c443b5eb3</citedby><cites>FETCH-LOGICAL-c372t-4e21212e4e2148efb226109fce83f85b70d019864cd4c56ab408a3a9c443b5eb3</cites><orcidid>0000-0002-7947-8642</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10103-017-2351-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10103-017-2351-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28990118$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Robati, Reza M.</creatorcontrib><creatorcontrib>Asadi, Elmira</creatorcontrib><creatorcontrib>Shafiee, Anoosh</creatorcontrib><creatorcontrib>Namazi, Nastaran</creatorcontrib><creatorcontrib>Talebi, Atefeh</creatorcontrib><title>Efficacy of long pulse Nd:YAG laser versus fractional Er:YAG laser in the treatment of hand wrinkles</title><title>Lasers in medical science</title><addtitle>Lasers Med Sci</addtitle><addtitle>Lasers Med Sci</addtitle><description>There are different modalities for hand rejuvenation. Fractional Er:YAG laser and long pulse Nd:YAG laser were introduced for treating hand wrinkles. We plan to compare fractional Er:YAG laser and long pulse Nd:YAG laser in a randomized controlled double-blind design with multiple sessions and larger sample size in comparison with previous studies. Thirty-three participants with hand wrinkles entered this study. They were randomly allocated to undergo three monthly laser treatments on each hand, one with a fractional Er:YAG laser and the other with a long pulse Nd:YAG laser. The evaluations included assessment of clinical improvement determined by two independent dermatologists not enrolled in the treatment along with measuring skin biomechanical property of hands using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT). Moreover, potential side effects and patients’ satisfaction have been documented at baseline, 1 month after each treatment, and 3 months after the final treatment session. Clinical evaluation revealed both modalities significantly reduce hand wrinkles (
p
value < 0.05), with no significant difference between two lasers. Mean CRRT values also decreased significantly after the laser treatment compared to those of the baseline in both laser groups. There was no serious persistent side effect after both laser treatments. Both fractional Er:YAG and long pulse Nd:YAG lasers show substantial clinical improvement of hand skin wrinkles with no serious side effects. However, combination treatment by these lasers along with the other modalities such as fat transfer could lead to better outcomes in hand rejuvenation. Trial registration: IRCT2016032020468N4</description><subject>Adult</subject><subject>Aged</subject><subject>Biomechanical Phenomena</subject><subject>Biomechanics</subject><subject>Clinical trials</subject><subject>Dentistry</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hand</subject><subject>Hand - radiation effects</subject><subject>Humans</subject><subject>Lasers</subject><subject>Lasers, Solid-State - adverse effects</subject><subject>Lasers, Solid-State - therapeutic use</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neodymium lasers</subject><subject>Optical Devices</subject><subject>Optics</subject><subject>Original Article</subject><subject>Patient Satisfaction</subject><subject>Photonics</subject><subject>Quantum Optics</subject><subject>Semiconductor lasers</subject><subject>Side effects</subject><subject>Skin</subject><subject>Skin Aging - 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radiation effects</topic><topic>Humans</topic><topic>Lasers</topic><topic>Lasers, Solid-State - adverse effects</topic><topic>Lasers, Solid-State - therapeutic use</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neodymium lasers</topic><topic>Optical Devices</topic><topic>Optics</topic><topic>Original Article</topic><topic>Patient Satisfaction</topic><topic>Photonics</topic><topic>Quantum Optics</topic><topic>Semiconductor lasers</topic><topic>Side effects</topic><topic>Skin</topic><topic>Skin Aging - radiation effects</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>YAG lasers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Robati, Reza M.</creatorcontrib><creatorcontrib>Asadi, Elmira</creatorcontrib><creatorcontrib>Shafiee, Anoosh</creatorcontrib><creatorcontrib>Namazi, Nastaran</creatorcontrib><creatorcontrib>Talebi, Atefeh</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aerospace Database</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Lasers in medical science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Robati, Reza M.</au><au>Asadi, Elmira</au><au>Shafiee, Anoosh</au><au>Namazi, Nastaran</au><au>Talebi, Atefeh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of long pulse Nd:YAG laser versus fractional Er:YAG laser in the treatment of hand wrinkles</atitle><jtitle>Lasers in medical science</jtitle><stitle>Lasers Med Sci</stitle><addtitle>Lasers Med Sci</addtitle><date>2018-04-01</date><risdate>2018</risdate><volume>33</volume><issue>3</issue><spage>461</spage><epage>467</epage><pages>461-467</pages><issn>0268-8921</issn><eissn>1435-604X</eissn><abstract>There are different modalities for hand rejuvenation. Fractional Er:YAG laser and long pulse Nd:YAG laser were introduced for treating hand wrinkles. We plan to compare fractional Er:YAG laser and long pulse Nd:YAG laser in a randomized controlled double-blind design with multiple sessions and larger sample size in comparison with previous studies. Thirty-three participants with hand wrinkles entered this study. They were randomly allocated to undergo three monthly laser treatments on each hand, one with a fractional Er:YAG laser and the other with a long pulse Nd:YAG laser. The evaluations included assessment of clinical improvement determined by two independent dermatologists not enrolled in the treatment along with measuring skin biomechanical property of hands using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT). Moreover, potential side effects and patients’ satisfaction have been documented at baseline, 1 month after each treatment, and 3 months after the final treatment session. Clinical evaluation revealed both modalities significantly reduce hand wrinkles (
p
value < 0.05), with no significant difference between two lasers. Mean CRRT values also decreased significantly after the laser treatment compared to those of the baseline in both laser groups. There was no serious persistent side effect after both laser treatments. Both fractional Er:YAG and long pulse Nd:YAG lasers show substantial clinical improvement of hand skin wrinkles with no serious side effects. However, combination treatment by these lasers along with the other modalities such as fat transfer could lead to better outcomes in hand rejuvenation. Trial registration: IRCT2016032020468N4</abstract><cop>London</cop><pub>Springer London</pub><pmid>28990118</pmid><doi>10.1007/s10103-017-2351-2</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-7947-8642</orcidid></addata></record> |
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| ispartof | Lasers in medical science, 2018-04, Vol.33 (3), p.461-467 |
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| language | eng |
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| subjects | Adult Aged Biomechanical Phenomena Biomechanics Clinical trials Dentistry Double-Blind Method Female Follow-Up Studies Hand Hand - radiation effects Humans Lasers Lasers, Solid-State - adverse effects Lasers, Solid-State - therapeutic use Male Medicine Medicine & Public Health Middle Aged Neodymium lasers Optical Devices Optics Original Article Patient Satisfaction Photonics Quantum Optics Semiconductor lasers Side effects Skin Skin Aging - radiation effects Time Factors Treatment Outcome YAG lasers |
| title | Efficacy of long pulse Nd:YAG laser versus fractional Er:YAG laser in the treatment of hand wrinkles |
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