Signaling pathway impact analysis by incorporating the importance and specificity of genes (SPIA-IS)

rlying biology of differentially expressed genes and proteins. Although various approaches have been proposed to identify cancer-related pathways, most of them only partially consider the influence of those differentially expressed genes, such as the gene numbers, their perturbation in the signaling...

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Veröffentlicht in:	Computational biology and chemistry 2017-12, Vol.71, p.236-244
Hauptverfasser:	Fang, Hongyuan, Li, Xianbin, Zan, Xiangzhen, Shen, Liangzhong, Ma, Runnian, Liu, Wenbin
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene expression profile Gene importance Gene specificity Signaling pathway analysis
Online-Zugang:	Volltext
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