KLF4 overcomes tamoxifen resistance by suppressing MAPK signaling pathway and predicts good prognosis in breast cancer

Tamoxifen resistance represents a daunting challenge to the successful treatment for breast cancer. Krüppel-like factor 4 has critical roles in the development and progression of breast cancer, but its expression, function and regulation in the efficacy of TAM therapy in breast cancer have yet to be...

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Veröffentlicht in:Cellular signalling 2018-01, Vol.42, p.165-175
Hauptverfasser: Jia, Yunlu, Zhou, Jichun, Luo, Xiao, Chen, Miao, Chen, Yongxia, Wang, Ji, Xiong, Hanchu, Ying, Xiaogang, Hu, Wenxian, Zhao, Wenhe, Deng, Wuguo, Wang, Linbo
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